Updates to Dr Bredesen's Protocol

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TheresaB
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Updates to Dr Bredesen's Protocol

Postby TheresaB » Wed Jun 12, 2019 9:26 am

I recently listened to this interview with Dr Bredesen Dr Dale-Bredesen and the End of Alzheimer's, How You can prevent it, and hope for all degenerative disease. The interview was posted at the end of May 2019, so it is very recent. I noted some differences in what he said in the interview and what he says in his book, The End of Alzheimer's. So when I had time I listened again and this time took notes. Differences noted:

    *He cites 6 types of Alzheimer's: (1) inflammatory (2) atrophic (1.5) glycotoxic (3) toxic (4) vascular and (5) traumatic. Vascular and traumatic are new since publication of his book

    *In his markers for glycotoxicity, he cites fasted insulin of 5.0 or lower (his book cites 4.5 or lower) and HbA1c of 4.5 to 5.2 (the book cites less than 5.6)

    *Dr Bredesen said that the Big Four to avoid are: grains, simple carbs, dairy, and lectins. Pro-inflammatory lectins have been added since publication of his book.

    * In his book, Dr Bredesen mentions the molds/mycotoxins: Stachybotrys, Penicillium, Aspergillus, Chaetomium. He has now added another: Wallemia.

I've also updated our Dr Bredesen Protocol Wiki
to notate these.
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Re: Updates to Dr Bredesen's Protocol

Postby CarrieS » Wed Jun 12, 2019 11:19 am

TheresaB wrote: I've also updated our Dr Bredesen Protocol Wiki
to notate these.

Thank you Theresa!
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Re: Updates to Dr Bredesen's Protocol

Postby Julie G » Wed Jun 12, 2019 2:09 pm

Thank you , Theresa! I'm pretty sure the fasting insulin was a misspeak and <4.5 still stands. The A1c is correct. The new goal is <5.3. There will be other updated goals in the new book. Dr. Bredesen has long spoke of the other two subtypes (vascular & traumatic) but I guess they didn't make the last book :?.

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Re: Updates to Dr Bredesen's Protocol

Postby thjj » Thu Jun 13, 2019 11:43 pm

Thank you—this is great! Did Dr. Bredesen mention anything about decaffeinated coffee? Is it ok for E4's to drink?
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Re: Updates to Dr Bredesen's Protocol

Postby TheresaB » Fri Jun 14, 2019 5:10 am

thjj wrote:Thank you—this is great! Did Dr. Bredesen mention anything about decaffeinated coffee? Is it ok for E4's to drink?


I don't recall him going into that much detail. He did mention he recommends a plant rich diet that he's found the phytonutrients to be good anti-Alzheimer’s nutrients and such things as anthocyanins and various polyphenols are quite helpful.
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Re: Updates to Dr Bredesen's Protocol

Postby Julie G » Fri Jun 14, 2019 7:45 am

thjj wrote:Thank you—this is great! Did Dr. Bredesen mention anything about decaffeinated coffee? Is it ok for E4's to drink?

Sneak peek from the new book: Coffee is great, associated with longevity and better cognition. Keep it under 4 cups so as not to increase homocysteine and before noon. It really does affect the quality of your sleep if you drink it later in the day. And, alcohol? We already know the E4 story. Overwhelming evidence suggests that it's particularly bad for our genotype. If you are going to cheat, go with an organic zero sugar, low alcohol dry red like that sold by Dry Farms Wine.

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Re: Updates to Dr Bredesen's Protocol

Postby NewRon » Fri Jun 14, 2019 10:13 am

Julie G wrote:
thjj wrote:Thank you—this is great! Did Dr. Bredesen mention anything about decaffeinated coffee? Is it ok for E4's to drink?

Sneak peek from the new book: Coffee is great, associated with longevity and better cognition. Keep it under 4 cups so as not to increase homocysteine and before noon. It really does affect the quality of your sleep if you drink it later in the day.


I'd imagine that's only if you metabolize caffeine. Some people don't have the gene to metabolize it (like me) and even a decaf Nespresso can affect sleep for up to two nights afterwards.

Dr Matthew Walker, the sleep neuroscientist, is very negative about coffee in general;

"Caffeine has a half-life of about six or seven hours. And a half-life simply means the amount of time it takes for a 50% of the drug to still be in your system or 50% of it to be cleared. Caffeine has a quarter life of about 12 hours. In other words, if you have a cup of coffee at noon, a quarter of that caffeine is still circulating in your brain at midnight.

So if you have a cup of coffee at noon, it's the equivalent of getting into bed at midnight. And just before you turn out the lights, you snick a quarter of a cup of Starbucks, and you hope for a good night of sleep, you know, it's probably not gonna happen.

So the advice would be; try to cut caffeine off around about midday if you can. And even if you're someone who, you know, can fall asleep fine, stay asleep, you should just know that caffeine can still impact your sleep."

https://www.foundmyfitness.com/episodes/matthew-walker
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Re: Updates to Dr Bredesen's Protocol

Postby Julie G » Fri Jun 14, 2019 10:21 am

I'd imagine that's only if you metabolize caffeine. Some people don't have the gene to metabolize it (like me) and even a decaf Nespresso can affect sleep for up to two nights afterwards.

Dr Matthew Walker, the sleep neuroscientist, is very negative about coffee in general;

"Caffeine has a half-life of about six or seven hours. And a half-life simply means the amount of time it takes for a 50% of the drug to still be in your system or 50% of it to be cleared. Caffeine has a quarter life of about 12 hours. In other words, if you have a cup of coffee at noon, a quarter of that caffeine is still circulating in your brain at midnight.

So if you have a cup of coffee at noon, it's the equivalent of getting into bed at midnight. And just before you turn out the lights, you snick a quarter of a cup of Starbucks, and you hope for a good night of sleep, you know, it's probably not gonna happen.

So the advice would be; try to cut caffeine off around about midday if you can. And even if you're someone who, you know, can fall asleep fine, stay asleep, you should just know that caffeine can still impact your sleep."

https://www.foundmyfitness.com/episodes/matthew-walker

Of course, you shouldn't drink caffeine if you can't tolerate it and Dr. Bredesen agrees that it should only be drunk before noon. (See above.)

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Re: Updates to Dr Bredesen's Protocol

Postby Creekside » Fri Jun 14, 2019 8:58 pm

So weird. My parents drank coffee from breakfast until shortly before bedtime, and they seemed to sleep like logs. Meanwhile, if I dare a cup of coffee at 1:30 pm, I most definitely feel an impact at bedtime.

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Re: Updates to Dr Bredesen's Protocol

Postby NewRon » Sat Jun 15, 2019 1:57 am

Of course, you shouldn't drink caffeine if you can't tolerate it and Dr. Bredesen agrees that it should only be drunk before noon. (See above.)


I actually think what he's gently saying, is that the science tells us that NOBODY can tolerate caffeine, irrespective of their genetic predisposition (and some metabolize less than others) and that it has an effect on everybody's sleep, whether we realize it or not.
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