'Strongest Evidence Yet' Links Anticholinergic Drugs, Dementia
"We found an obvious dose-response relationship between anticholinergic drug use and risk of developing dementia: the higher the usage, the greater the risk," Dr Gray commented to Medscape Medical News.
Even Low Doses Implicated
But people taking just the minimum effective dose of these agents for prolonged periods qualified as having high use and were found to be at greater risk for dementia compared with those not taking such medicines.
"This is not excessive use," Dr Gray said. "Many of these agents are used chronically, and chronic use — even at low doses — would put you in the highest risk category."
While on Medscape I also noticed these related articles:
Just 2 Months' Exposure to Anticholinergics Affects Cognition
Pain Patients at Cognitive Risk From Anticholinergic Burden?
Here's a link to Silverlining's topic listing common anticholinergics:
List of Anticholinergic Drugs with Burden Assessment