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Living on the Edge: Moderately Low Aβ42 in CSF Predicts Decline

Posted: Mon Mar 23, 2015 9:46 pm
by circular
"Researchers have set a threshold for Aβ in the cerebrospinal fluid of 192 pg/ml—anything less indicates Alzheimer’s disease pathology has begun. Now, a report suggests that people who are just above that cutoff are highly likely to dip below it within three years.

"Alone, cognitive scores, hippocampal volume, ApoE status, and CSF levels of total or phospho-tau did not vary significantly between the two groups. Ultimately, the most powerful predictor of decline emerged when researchers considered p-tau, Aβ42, and ApoE status together."

http://www.alzforum.org/news/research-n ... ts-decline

Now when are they going to develop a pain-free way to test CSF??? Anyone working on THAT?