Inhalational Alzheimer's?

Alzheimer's, cardiovascular, and other chronic diseases; biomarkers, lifestyle, supplements, drugs, and health care.
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SusanJ
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Re: Inhalational Alzheimer's?

Postby SusanJ » Fri May 27, 2016 8:44 am

Well said Bernie! We're all pulling for you Julie to get to the root cause! Hugs.

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Re: Inhalational Alzheimer's?

Postby Tincup » Fri May 27, 2016 9:49 am

(((Julie)))

I just dropped in here and haven't read the whole thread, but here are some ideas.

I know little about Lyme, but have listened to Tim Ferris and Dave Asprey on this. Some things to throw in the hopper. Tim says his mental function was greatly helped by ketosis.

Here is a podcast with Rhonda https://www.youtube.com/watch?v=w3KuJVni5zQ The transcript is here http://www.foundmyfitness.com/timtranscript. His Lyme discussion starts on p 13. Tim thinks that the reoccurring Lyme symptoms may be related to a devastated gut biome from the antibiotics used to treat the Lyme...

Dave interviews Tim here: https://www.bulletproofexec.com/tim-ferriss-injury-lyme-disease-filming-tim-ferriss-experiment-215/ and the Lyme starts at 23:44. Dave also mentions about fungus in the gut.

Dave thinks his mitochondria were damaged by mold exposure and he needs to be in mild ketosis to function (sound familiar?) He talks about this in his interview with Richard Veech (ketone expert at NIH). https://www.bulletproofexec.com/exclusive-interview-with-ketone-expert-dr-richard-veech-299/ Dave sells a caprillic acid (C8) supplement he calls "Brain Octane." From what I understand, C8 is the most potent of the MCT's, from a ketone perspective.

On the antibiotics, Theresa had surgery five weeks ago and was prescribed antibiotics. Rhonda says VSL#3 has the most data behind it and the sachets are the most potent for prebiotics. So I ordered two months worth of this for each of us. I've also had plenty of antibiotics, including a very strong one from the dentist not that long ago. I also think I was messing with my biome by consuming daily magnesium chloride water to keep my afib in line - did this for years. I subsequently switched to a form of mag that doesn't mess with the biome. In any case, VSL#3 is expensive and should be shipped on ice. The company I ordered from is http://www.sundropsonline.com/VSL_p/745749017802.htm and they do ship with ice packs and they only ship Mon-Wed with two day shipping so it doesn't sit around over the weekend. We mix the VSL with water without chlorine and also mix in inulin, glucomannan, psyllium husks and modified citrus pectin as prebiotics to help feed the bugs.

Dr. Perlmutter, in "Brain Maker," suggests possibly using a probiotic enema. I've tried this with a couple of sachets.

TRY A PROBIOTIC ENEMA, WITH PERMISSION This won’t be for everyone, but I can’t tell you how many patients have benefited from this at-home procedure. It’s the best way to introduce probiotic bacteria directly into the bowel. Enemas, one of the oldest remedies on the planet and dating back to the ancient Egyptians and Mayans, are used to flush out the lower bowel by injecting fluid into the rectum. (The word enema is Greek for “inject.”) They are also used to administer certain medicinal therapies directly into the colon. It’s imperative that you get clearance from your doctor before using an enema so that you don’t harm yourself. Once you’ve gotten the go-ahead, here’s what you’ll need: • Enema bag • 3– 6 probiotic capsules or 1/ 8 teaspoon powdered probiotic (Make sure they include bifidobacteria, as these are the dominant flora in the colon, whereas acidophilus prefer the small intestine.) • Filtered (chlorine-free) water • Lubricant (optional) • Privacy Plan to perform your enema in the morning after having a bowel movement. Fill a large cup with 12 ounces of lukewarm, filtered water. Break open the probiotic capsules and empty the probiotics into the water, stirring to dissolve. Fill the enema bag with the probiotic mixture, and close the bag using the clamp that comes with the device. Lie down flat on your side (either side is fine) on a towel or in the bathtub. Insert the nozzle tip into your rectum (use a lubricant if that helps). Holding the bag higher than the nozzle, release the clamp so the water flows into the colon. Try to hold the enema for 30 minutes if possible. How often I recommend this procedure depends on the specific needs of the patient. In someone who has had aggressive antibiotic therapy, for example, I’d prescribe probiotic enemas as often as three times weekly for 4 to 6 weeks and then reassess the situation. Your personal treatment plan will depend on your own situation; ask your healthcare provider for a recommendation.

Perlmutter, David (2015-04-28). Brain Maker: The Power of Gut Microbes to Heal and Protect Your Brain for Life (pp. 211-212). Little, Brown and Company. Kindle Edition.

My gut is better, and cutting out the MgCl2 in November 2015 did make a big difference, but the VSL has helped incrementally (I was taking other prebiotics before starting the VSL). I now feel like by bowels are fairly normal for the first time in a long time.
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Re: Inhalational Alzheimer's?

Postby circular » Fri May 27, 2016 11:06 am

buck3Maureen wrote:Circ - at the risk of giving you one more useless solution - I can say what worked for me. A product that is sold by Life Extension called "Immune Modulator". I take one pill AM and one PM. It is an Ayervedic rememdy called Tinispora Cordifolia. You can buy it in bulk and it is the same stuff. So I have no real problems anymore -- no infections for the last 10 years. No waking up choking. I just have a little stuffy feeling in my nose. Takes a week or two to kick in. If I miss a day I notice it right away.

Maureen, sorry I forgot to get back and reply to this. I need a way to hold posts for later reply when I'm too busy. When I first scanned your post I was thinking Tiniipora Cordifolia was just for sinus infections, which I don't get. Too bad I was rushed at the time, I finally looked it up at Examine.com and see why you suggested it! Sheesh, wish I'd been trying that during this years allergy season. It also may have mast cell stabilizing properties.

Interestingly, under interactions it says:
8.1. Bacopa and Evolvulus
Bacopa monnieri (Brahmi) and Evolvulus alsinoides (Shankhapushpi) are two ayurvedic herbs used for the purpose of cognitive enhancement. While both of them individually (at 200mg/kg oral ingestion to rats with amnesia) are more effective than tinospora cordifolia and any pair merely suggests that bacopa monnieri is the most potent single herb, the combination of all three herbs at a combined 200mg/kg appears to be most effective which suggests synergism.[49] [Emphasis added]

https://examine.com/supplements/tinospora-cordifolia/

Maybe for someone with lots of allergic-type reactions and mast cell over-activity and e4 and/or memory issues this combination is worth exploring. Bacopa comes up a lot and is in Dr. Bredesen's protocol.

This appears to be a powerful herb with many potential effects, making it one to both consider and be cautious of?

Thanks Maureen!
ApoE 3/4 > Thanks in advance for any responses made to my posts.

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Re: Inhalational Alzheimer's?

Postby Julie G » Fri May 27, 2016 11:34 am

George, thanks for your thoughts. This has come out of left field for me :?. I thought I was just humoring Dr. B. by doing the CIRS testing, but he was getting increasingly persistent and annoyed with me for not following through. When my IgG dropped again AND I started getting chronic bladder infections, I realized I was getting into serious trouble and had to get to the bottom of things. At this point, you could still knock me over with a feather- Lyme disease???

According to Dr. B., I was treated appropriately 6 years ago IF I had not had the HLA haplotype that made me susceptible to chronic Lyme. And, he concurs with everything you just shared. He says my consistent ketosis, low amalyse & no grain diet, biomarker optimization, and supplements have already been fighting this... but wouldn't be enough over the long haul. I think I do have major antibiotics to face in my near future. I'm already taking VSL-3 and will consider various routes :shock: as I move along on my journey. XO

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Re: Inhalational Alzheimer's?

Postby circular » Fri May 27, 2016 11:55 am

Juliegee wrote:I think I do have major antibiotics to face in my near future...

Jeez'l Pete, or however that's spelled. I hope you're okay and that doesn't mean surgery. No rest for you, but I think the silver lining is that now you will be able to achieve greater health perhaps than anything you've felt for many years.

I'm now curious whether the Tinospora cordifolia Maureen mentioned, as a potential (I can't vouch for all the claims) immune modulator/adaptogen/mast cell stabilizer, might be useful in this context of CIRS and type III AD if not lyme. Lyme specifically isn't mentioned on TC's Examine.com page. However, this page mentions it for when lyme includes joint involvement (https://saiayurvediccollege.com/ayurved ... e-disease/)
ApoE 3/4 > Thanks in advance for any responses made to my posts.

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KatieS
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Re: Inhalational Alzheimer's?

Postby KatieS » Fri May 27, 2016 2:03 pm

Julie, interesting how these nasty pathogens might be the culprit. Decades ago, my husband had Lyme with antibiotic treatment. Very complicated so it's great that you'll be seeing a specialist. We're sending positive thoughts.

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Re: Inhalational Alzheimer's?

Postby buck3Maureen » Fri May 27, 2016 4:47 pm

Hi Circular,
Regarding the tinospora cordifolia (sold by Life Extension as Immune Modulator). I don't believe this is a real fix for anything. I suffer from chronic rinosinusitus and read in the LE literature that it had helped some - I tried it and it worked for me. What I mean by 'worked' is that the symptoms of the sinusitus are reduced - so that I don't get sinus infections. However the stuffines is still there but reduced. I recently found that my TGF Beta one is double what it is supposed to be and I am waiting for a phone appt with Dr. Bredesen. I am hoping that whatever treatment is proposed could actually correct the problem.

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Re: Inhalational Alzheimer's?

Postby Silverlining » Sun May 29, 2016 4:43 am

Just seeing this Julie....wow...good/bad for sure....horrible about the levels, but great that you finally tested and can now do something about it! Love you Julie....keep your spirits up and remember to find your zen every day, if possible!

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Re: Inhalational Alzheimer's?

Postby buck3Maureen » Sun Jun 12, 2016 9:37 am

For all of us that are concerned about Inhalation AD. I was able to have a phone appt with Dr. Bredesen. Since I have high TGF Beta1 and a history of getting Chronic sinusitus right have exposure to mold - He has recommended a Dr. in Atlanta who is an expert in this. He said that he wil be able to determine by looking at my sinuses (sorry for all the bad spelling) whether I have an on going infection or the residual inflamation. Evidently - if I understand this correctly - both can be treated, but you must deal with the infection first if present. I don't want to get my hopes up too high but this could mean, if I really am understanding this, that I could get rid of my sinus problem. My appt is the end of this month - I'll let you know what I find out. By the way there is also a urine test by a company called Real time Data - I think called SPM active that will determine if you have an active infection.

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Re: Inhalational Alzheimer's?

Postby TheBrain » Sun Jun 12, 2016 11:40 am

Maureen, good luck with your appointment with this new doctor in Atlanta. I hope your sinus problem finally resolves and that resolving the active infection or the residual inflammation from it (whichever the case may be) helps with your other issues.

I am awaiting the results of my CIRS testing. My blood draw was three weeks ago last Friday. I was told by a woman at National Jewish Health that my C4a test results should be available by mid-June. Hopefully, I'll get all my results next week.

I decided to hold off on the VCS eye test until I get my CIRS results. I'm homozygous for that worrier gene, so I figured I'd wait.
ApoE 4/4 - When I was in 7th grade, my fellow students in history class called me "The Brain" because I had such a memory for detail. I excelled at memorization and aced tests. This childhood memory helps me cope!


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