Sweet drug clears cholesterol, reverses heart disease—and was found by parents

Alzheimer's, cardiovascular, and other chronic diseases; biomarkers, lifestyle, supplements, drugs, and health care.

GenePoole0304
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Re: Sweet drug clears cholesterol, reverses heart disease—and was found by parents

Postby GenePoole0304 » Fri Apr 08, 2016 8:30 pm


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Russ
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Re: Sweet drug clears cholesterol, reverses heart disease—and was found by parents

Postby Russ » Sat Apr 09, 2016 7:00 am

A very interesting development....
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Eat whole, real, flavorful food - fresh and in season... and mix it up once in a while.

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thumperama
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Re: Sweet drug clears cholesterol, reverses heart disease—and was found by parents

Postby thumperama » Mon Apr 11, 2016 11:25 am

There has been some previous discussion about cyclodextrin on the forums:

https://www.apoe4.info/forums/search.php?keywords=cyclodextrin

This clearly renews my interest.

Does anyone have access to the full text? I'm going to contact the author.

The following links to an article in Popular Science. Apparently cyclodextrin is used in powered alcohol. See the arterial imaging from the 12-week study. Fascinating.

http://www.popsci.com/compound-in-powdered-alcohol-can-also-treat-clogged-blood-vessels

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GenePoole0304
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Re: Sweet drug clears cholesterol, reverses heart disease—and was found by parents

Postby GenePoole0304 » Mon Apr 11, 2016 12:49 pm

here is more that was explored at www.heartlifetalk.com

http://www.ncbi.nlm.nih.gov/pmc/article ... 990773.pdf

to access 2 pdf files one should signup, we have been exploring the issue for a while there

http://www.heartlifetalk.com/forums/def ... #post89617

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Julie G
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Re: Sweet drug clears cholesterol, reverses heart disease—and was found by parents

Postby Julie G » Mon Apr 11, 2016 4:14 pm

Thanks for sharing, Schnooks. Thanks also to Chris & Gene for the links. I've long been interested in cyclodexetrin for our population. I still wonder how or if it would affect ketosis...

It almost sounds too good to be true. Two forbidden fruits (sweet stuff in powdered alcohol) that lowers our cholesterol? Make mine cabernet flavored, please :lol:

GenePoole0304
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Re: Sweet drug clears cholesterol, reverses heart disease—and was found by parents

Postby GenePoole0304 » Mon Apr 11, 2016 6:08 pm

"I still wonder how or if it would affect ketosis..."

I would doubt it as it just locks out saturated fat, the alpha form but certainly is worth trying as it helps BG control too.
Try it a month before doing a nmr lipid profile.


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Re: Sweet drug clears cholesterol, reverses heart disease—and was found by parents

Postby Harrison » Tue Apr 12, 2016 9:29 am

They used apoE-deficient mice:

To investigate the efficacy of CD treatment in murine atherosclerosis, apolipoprotein E (ApoE−/−) deficient mice were fed a cholesterol-rich diet and concomitantly treated subcutaneously with CD or vehicle control for 8 weeks. Although plasma cholesterol, the main driver of atherosclerosis, remained unaffected (Fig. 1A), CD treatment profoundly reduced atherosclerotic lesions within the aortic root (Fig. 1B)


It's also interesting that they think that Liver X receptor (LXR) reprogramming is the mechanism of action. This has long been researched as an approach for treating Alzheimer's disease, but toxicity problems have stopped it from ever getting traction.

Not surprisingly, people are considering cyclodextrins for AD:
http://www.ncbi.nlm.nih.gov/pubmed/27037956
http://www.ncbi.nlm.nih.gov/pubmed/24813313
http://www.ncbi.nlm.nih.gov/pubmed/23209315

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Re: Sweet drug clears cholesterol, reverses heart disease—and was found by parents

Postby ApropoE4 » Wed Apr 13, 2016 4:07 pm

Finally, a good use for Febreze.


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