Stavia, I'm kinda amazed how one little variant (like that B12 "thingy") can cut your hcy in half. Awesome. And Katie, I'm with you, stuck at an hcy of 10. Supplementing w/800mcg methylfolate, 33mgs P5P and 1000mcg methylcobalamin, & have just upped my TMG from 500 to 700mgs. Last test my B12 was over 1800 (pg/mL), so not the problem. I'm thinking about adding some SAM-e, but a bit hesitant..
According to Genetic Genie, I'm: homozygous for MAO-A R297R, MTRR A66G, CBS A360A
heterozygous for: COMT V158M, COMT H62H, MTRR A664A, BHMT-02, MHMT-08, VDR Bsm &VDR Taq
Any comments/suggestions would be welcome! My doc has told me twice now (so I need to drop it w/her) that she can't get anyone below 10 in her practice.