http://www.agingbraincare.org/uploads/p ... l_size.pdf
venlafaxime is a level 1 anticholinergic. i know i am very sensitive to anticholinergics because before i knew about their detrimental effects, i took a half a tablet of benadryl (15mg?) 3 days a week to help me sleep through hot flashes. it did help me sleep, but by the end of the week i could not string a sentence together and kept slurring words. benadryl is a level 3 anticholinergic, along with a lot of other meds used for hot flashes.
i strongly recommend that anyone with concerns about hypo metabolism in the brain double check all their meds, including OTC meds, with the list of anticholinergic meds i linked to. once i had a little diarrhea and amazingly I had a great night's sleep after taking it. I checked the anticholinergic meds list and, guess what, that anit-diarrhea med (Lomotil) was on it.