Ashwaganda and curcumin have some data in cell culture and/or in mice showing beneficial effects in reducing amyloid, but I don't expect we'll ever see a randomized, double-blinded, placebo-controlled human trial with amyloid imaging to conclusively demonstrate this. In the end, if one decides to take these, the best they can do is try to use reputable companies that actually sell what they say they are selling, and hope for the best.
The people who took curcumin experienced significant improvements in their memory and attention abilities, while the subjects who received placebo did not, Small said. In memory tests, the people taking curcumin improved by 28 percent over the 18 months. Those taking curcumin also had mild improvements in mood, and their brain PET scans showed significantly less amyloid and tau signals in the amygdala and hypothalamus than those who took placebos
Looking into if I should switch from Longvida to Theracurmin.
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