Hi again Karen and Walt, Frank touches on a very interesting possibility, although an expensive one, when he mentions Dr Shoemaker's RNA sequencing approach to CIRS/mold/biotoxin evaluation. I can't vouch for how well validated his interpretations are (I suspect not very well yet?), but he presents this as pretty much the next generation for biotoxin testing that is much more precise than the boatloads of blood work (although maybe they're used together?).
I am very tempted to do it myself to get first hand experience with it, because I have a lot of different viruses in my blood work, some with high titres. He claims that the RNA sequencing will tell me whether or not they are indeed active and if so which ones, which the blood results can't do (even perhaps when the levels are high?). In addition, I think that rather than just say what one's HLA SNPs are, the RNA sequencing would tell you wether those SNPs are activated (?).
I think the test is about US $1500 and requires repeats. Ugh! http://www.survivingmold.com/news/2017/ ... ty-part-1/
(see the link to part two at the end). I'll try to find an interview with Dr. Shoemaker I heard about this. It's in our forum archives.
You might contact Dr Shoemaker and see if there is someone local to you who has trained with him. Also, maybe the RNA approach is both more available to you and yields better data (?). The biggest drawback may be that it hasn't been widely tested and validated, although many would say his original protocol isn't either. I find the comments about VIP in part 2 at Shoemaker's website are very interesting.
Our group has published two papers on genomics, with the first in 2015 on the chronic inflammatory response syndrome (CIRS) seen in ciguatera and the more recent paper, a landmark study showing existence and correction by VIP (after the antecedent steps in our protocol are completed) of a host of gene activation abnormalities seen in CIRS caused by exposure to the interior environment of water damaged buildings (CIRS-WDB). This paper also included the absolutely stunning finding that the use of VIP dramatically changes genes controlling function of both ribosomes and mitochondria, possibly revealing the main sources of chronic fatiguing illness. Incredible. Recall that ribosomes serve as the intracellular site of protein synthesis (the place where RNA initiates production of polypeptides and proteins), and mitochondria produce cellular energy in the form of ATP. For the first time, ever, a patient can be tested to show us definitely what is actually happening with the CIRS illnesses and the genomic, transcriptomic and proteomic consequences.
ApoE 3/4 > Thanks in advance for any responses made to my posts.