https://www.sciencedaily.com/releases/2 ... 132526.htmThe encouraging results led the researchers to test NR (nicotinamide riboside) in a mouse model of Alzheimer's disease. Just like C. elegans, the mice saw a significant improvement of mitochondrial function and a reduction in the number of amyloid plaques. But most importantly, the scientists observed a striking normalization of the cognitive function in the mice. This has tremendous implications from a clinical perspective.
According to Johan Auwerx, tackling Alzheimer's through mitochondria could make all the difference. "So far, Alzheimer's disease has been considered to be mostly the consequence of the accumulation of amyloid plaques in the brain," he says. "We have shown that restoring mitochondrial health reduces plaque formation -- but, above all, it also improves brain function, which is the ultimate objective of all Alzheimer's researchers and patients."
Nicotinamide riboside
Nicotinamide riboside
This is a mouse study, but interesting results targeting mitochondrial health.
