Regarding Kidney disease your kidney's aren't working correctly and therefore you can't excrete aluminum. Vitamin D will help the elimination of aluminum. If you want any of these references please contact me.
"Beyond its prevention of rickets, vitamin D has been shown to facilitate the lowering of aluminum levels in the serum of children and the bones, liver, and brain of rats with high levels of aluminum due to kidney disease289,608. Kidney disease results in both lower levels of vitamin D and higher levels of aluminum in serum. During 2009, 10 pediatric patients with kidney disease and 20 healthy controls were studied. It was found that 4 weeks of active vitamin D supplementation (not D3 supplementation) at a level of 15-45ng/kg/day (dosed according to their parathyroid hormone levels) resulted in serum aluminum concentrations declining from a median level of 27.2ng/ml to 3.8ng/ml as compared with a median level of 2.5ng/ml for healthy controls289. There was also a reversal of high aluminum levels in the tissues, including the brains, of the children with kidney disease304,609. Figure 9 emphasizes this dramatic reversal:
Figure 9 – Vitamin D lowers elevated aluminum levels in children289
Kidney disease frequently goes undiagnosed. This can be because a marker for kidney disease, parathyroid hormone – PTH, at first enhances aluminum absorption and aluminum accumulation in the brain and bones304,305. Once the aluminum levels get sufficiently high in the parathyroid gland, the aluminum disguises the kidney disease by then inhibiting PTH production by the parathyroid gland610. Aluminum also inhibits the production of active vitamin D from D2 in the kidneys of rats, dogs, and humans300,301,611. Therefore aluminum absorption may be one of the reasons for the prevalence of active vitamin D deficiency in the U.S. population302."
289. Azik, F.M., et al.; A different interaction between parathyroid hormone, calcitriol, and serum aluminum in chronic kidney disease; a pilot study; Int. Urol. Nephrol.; 43:467-470 (2011)
301. Goodman, W.G., et al.; Parenteral aluminum administration in the dog II. Induction of osteomalcia and effect on vitamin D metabolism; Kidney Int.; 25:370-75 (1984)
302. Adit, A., et al.; Demographic differences and trends of vitamin D insufficiency in the US population, 1988-2004; Arch. Intern. Med. 169(6):626-632 (2009)
304, Mayor G.H., et al.; Parathyroid hormone-mediated aluminum deposition and egress in the rat; Kidney Int.; Jan.; 17(1):40-4 (1980)
305. Constantini, S.; Distribution of aluminum following intraperitoneal injection of aluminum lactate in the rat; Pharmacol. Oxicol.; Jan.; 64(1):47-50 (1989)
608. Hershberg, R.; et al.; Organ distribution of aluminum in uremic rats: influence of parathyroid hormone and 1,25-dihydroxyvitamin D3; Miner Electrolyte Metab.; 11:106-110 (1985)
609. Mayor, G.H., et al.; Impaired renal function and aluminum metabolism; Fed. Proc.; Oct.; 42(13):297-83 (1983)
611. Klein, G.L., et al.; Serum levels of 1,25-dihyroxyvitamin D in children receiving parenteral nutrition with reduced aluminum content; J. Pediatr. Gastroenterol. Nutr.; Feb.; 4(1):93-6 (1985)
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Last edited by laurie
on Fri Jan 12, 2018 7:30 am, edited 1 time in total.
"True prevention is only possible by first discovering the cause of a disease such as Alzheimer's."
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