Copied from the article listed by Schwartz336:
"Available data have shown that patients with a diagnosis of MCI, whatever the cause, had improvements or stabilization of cognitive decline, whereas the results in patients diagnosed with AD or vascular dementia, although evaluated in small samples, did not show evidence of benefit following treatment with homotaurine."
The mini mental status exam (MMSE) was the tool used to determine improvement over one year. Those with amnesic MCI improved from a MMSI of 24 to 26 (out of 30). Those with non-amnesic single and multi-domain MCI improved at month 4, then slowly declined.
Interestingly, at the beginning of the trial, "all patients underwent a complete clinical investigation, including medical history, neurological examination, mini mental state examination (MMSE), a complete blood screening (including routine exams, thyroid hormones, level of B12), neuropsychological examination, neuropsychiatric evaluation, and neuroimaging consisting of magnetic resonance imaging (1.5 T MRI)." Too bad they didn't repeat the neuropsych evals throughout the year, since it a more accurate test of cognition in comparison to the MMSE.