shacherry wrote:Anyone know what's going on here.
Plumster wrote:I've read that decreased estrogen can raise homocysteine. Could a decrease in male hormones cause a similar effect? Just a thought with no scientific backing.
shacherry wrote:The only medicine changes are now I am on spironolactone that can lower blood pressure...
SusanJ wrote:shacherry wrote:The only medicine changes are now I am on spironolactone that can lower blood pressure...
From a quick check, spironolactone needs SAMe to be metabolized.
SAMe of course is created from B vitamins via the methylation cycle, so you are now using up extra B vitamins to metabolize spironolactone that in the past would have been used to recycle homocysteine.
You'll likely need to boost your Bs. Maybe try adding 400 mcg folate and 500 mcg B12 and retest in a few weeks. If that doesn't work, talk to your doctor about what you're experiencing.
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