VieLight

Alzheimer's, cardiovascular, and other chronic diseases; biomarkers, lifestyle, supplements, drugs, and health care.
NewRon
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Re: VieLight

Post by NewRon »

Apo E4/E4, Male, Age 60
bladedmind
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Re: VieLight

Post by bladedmind »

swampf0etus wrote:I recommend you read the Device Watch (a Quackwatch subsidiary site) report on LLLT here: https://www.devicewatch.org/reports/lllt.shtml and the Science Based Medicine article here: https://sciencebasedmedicine.org/lower- ... in-action/

As to "far-infrared sauna", your reference is to an article on saunas, not far-infrared saunas. Some small studies on infrared saunas have found some small benefits, probably placebo effect. If you're willing to spend the money, they won't harm you but you may not feel any benefit. https://www.mayoclinic.org/infrared-sau ... q-20057954
Thank you. I explicitly did not advocate LLLT, I only pointed out that the “swindle” you referenced pertained to an entirely different kind of device. I claimed that you provided mistaken information, and you did not respond to that claim.

One should be skeptical, including of extreme skepticism. I find Quackwatch mildly useful but its exaggerated scientism strikes me as a substitute religion in its certainty, fervor, and zeal to police heresy. And the website “Science-Based Medicine” you cite ridicules, for instance, the usage of routine vitamin supplementation, vitamin D supplementation, curcumin, coffee bean extract, fish oil, coconut oil, green tea, glucosamine, chondroitin, MSM, MTFHR genetic testing, avoidance of artificial sweeteners. considers functional medicine harmful and dangerous, etc. By the standards of the two cited authorities, Bredesen, Gundry, and most of this board, would be found guilty and excommunicated. I’m against gullibility and quackery, but also I reject the idea of the scientific priesthood vs. the superstitious peasants.

Your link is to an FDA letter to an obvious charlatan selling LLLT. ‘There are legitimate scholars who differ from your sources. See the Wellman Center for Photomedicine: http://wellman.massgeneral.org/about.htm. Affiliate Prof. Michael Hamblin at Harvard Medical School studies, among other things,
Low-level light therapy (LLLT) (light alone, no photosensitizer) can stimulate healing, prevent tissue death and relieve pain and inflammation. The molecular and cellular mechanisms that underlie this effect are under investigation. We believe that reactive oxygen species are also involved and cause activation of redox sensitive transcription factors. Stem cells are particularly susceptible to the effects of light and can be induced to differentiate and proliferate. Light-sensitive ion channels are another possible cellular pathway. Applications of LLLT to healing and treatment of traumatic brain injury are being studied. Results from these studies have suggested that transcranial near-infrared (NIR) light may have wide applications to a diverse range of brain disorders, including stroke, neurodegenerative diseases such as Alzheimer’s and Parkinson’s, psychiatric disorders such as depression, anxiety, PTSD, autism, and addiction.

Dr. Hamblin has published over 289 peer-reviewed articles, over 150 conference proceedings, book chapters and international abstracts, and he holds eight patents. He has edited the most recent and comprehensive textbook on PDT entitled "Advances in Photodynamic Therapy: Basic, Translational and Clinical". He also co-edited a book entitled "Photodynamic Inactivation of Microbial Pathogens: Medical and Environmental Applications", an authoritative and comprehensive textbook entitled "Handbook of Photomedicine" with 70 chapters and 800 pages, a textbook entitled "Applications of Nanoscience in Photomedicine" and another comprehensive handbook called "Handbook of Low Level Laser (Light) Therapy" is in press. Four other textbooks are in progress.
As to saunas, yes, I cited a study about saunas and dementia, not specifically infrared saunas. Guilty! I said saunas are probably good for your health, and that my infrared sauna makes me feel good, but I was cautious about health claims. Apparently, the pleasure I get from using a sauna is not a sufficiently scientific benefit for me to have bought one.
bladedmind
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Re: VieLight

Post by bladedmind »

Apologies, this will be my last post on the topic.

10-minute search:

http://www.jneuropsychiatry.org/peer-re ... isease.pdf
Neuropsychiatry (London) (2018) 8(2), 477–483
Transcranial Low-Level Laser Therapy for Depression and Alzheimer’s Disease

https://www.sciencedirect.com/science/a ... 3717300744
Alzheimer's & Dementia: Translational Research & Clinical Interventions
Volume 4, 2018, Pages 54-63
Neuroprotective effect of a new photobiomodulation technique against Aβ25–35 peptide–induced toxicity in mice: Novel hypothesis for therapeutic approach of Alzheimer's disease suggested

https://www.ncbi.nlm.nih.gov/pubmed/28735143
Neurobiol Aging. 2017 Oct;58:140-150. doi: 10.1016/j.neurobiolaging.2017.06.025. Epub 2017 Jul 6.
Transcranial low-level laser therapy improves brain mitochondrial function and cognitive impairment in D-galactose-induced aging mice.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568598/
Photomed Laser Surg. 2017 Aug 1; 35(8): 432–441. doi: 10.1089/pho.2016.4227
Significant Improvement in Cognition in Mild to Moderately Severe Dementia Cases Treated with Transcranial Plus Intranasal Photobiomodulation: Case Series Report

https://www.ncbi.nlm.nih.gov/pubmed/28735143
J Photochem Photobiol B. 2017 Mar;168:149-155. doi: 10.1016/j.jphotobiol.2017.02.008. Epub 2017 Feb 13.
Treating cognitive impairment with transcranial low level laser therapy.

https://www.ncbi.nlm.nih.gov/pubmed/26817446
Lasers Surg Med. 2016 Apr;48(4):343-9. doi: 10.1002/lsm.22471. Epub 2016 Jan 12.
Transcranial laser stimulation improves human cerebral oxygenation.

https://www.ncbi.nlm.nih.gov/pubmed/24994540
J Mol Neurosci. 2015 Feb;55(2):430-6. doi: 10.1007/s12031-014-0354-z. Epub 2014 Jul 4.
Low-level laser therapy ameliorates disease progression in a mouse model of Alzheimer's disease.

https://www.frontiersin.org/articles/10 ... 00036/full
Front. Syst. Neurosci., 14 March 2014 | https://doi.org/10.3389/fnsys.2014.00036
Augmentation of cognitive brain functions with transcranial lasers
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Re: VieLight

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bladedmind wrote:Apologies, this will be my last post on the topic.
Thanks for your posts!
Tincup
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Re: VieLight

Post by bladedmind »

https://www.ncbi.nlm.nih.gov/pubmed/31050946
https://www.liebertpub.com/doi/pdf/10.1 ... .2018.4569
Photobiomodul Photomed Laser Surg. 2019 Mar;37(3):159-167. doi: 10.1089/photob.2018.4569.
Rapid Reversal of Cognitive Decline, Olfactory Dysfunction, and Quality of Life Using Multi-Modality Photobiomodulation Therapy: Case Report.
Salehpour F1,2,3, Hamblin MR4,5,6, DiDuro JO3,7.
Objective: We present a case report of reversal of cognitive impairment, olfactory dysfunction, and quality of life measures in a patient with cognitive decline after multi-modality photobiomodulation (PBM) therapy. Background: Transcranial and intranasal PBM has been introduced as a light-based therapeutic technique in which exposure to low levels of red to near-infrared (NIR) light stimulates neuronal function, leading to beneficial neurological effects. Materials and methods: Patient received twice-daily PBM therapy at home using three different wearable light-emitting diode (LED) devices. For the first week containing a mixture of continuous wave mode red (635 nm) and NIR (810 nm) LEDs, a prototype transcranial light helmet and a body pad were used. The body pad was placed on various areas on the lower back and the helmet was worn while seated. After the first week of treatment, an intranasal LED device, 10-Hz pulsed wave mode NIR (810 nm), was initiated in the left nostril twice daily. All three devices were applied simultaneously for an irradiation time of 25 min per session. Results: The patient showed a significant improvement in the Montreal Cognitive Assessment score from 18 to 24 and in the Working Memory Questionnaire score from 53 to 10. The cognitive enhancement was accompanied by reversal of olfactory dysfunction as measured by the Alberta Smell Test and peanut butter odor detection test. Quality-of-life measures improved and caregiver stress was reduced. No adverse effects were reported. Conclusions: PBM therapy may be a promising noninvasive approach for patients with neurodegenerative diseases.
https://i.imgur.com/GhKoLjNh.png

Published, remarkable, n=1 study of PBM intervention on early-Alzheimer's patient. I am not competent to evaluate it, and welcome advice.

Also:
https://www.liebertpub.com/doi/abs/10.1 ... .2018.4555
Photobiomodul Photomed Laser Surg. 2019 Mar;37(3):133-141
Effects of Home Photobiomodulation Treatments on Cognitive and Behavioral Function, Cerebral Perfusion, and Resting-State Functional Connectivity in Patients with Dementia: A Pilot Trial.
Conclusions: Because PBM was well tolerated and associated with no adverse side effects, these results support the potential of PBM therapy as a viable home treatment for individuals with dementia.
An informative but disorganized and worrisomely exuberant thread here: https://www.longecity.org/forum/topic/1 ... ted/page-1
More cogent discussions elsewhere, but the thread has many links, some of them good.
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