I have started supplementing with this as recommended in Dr. Bredesen's book. Anyone else trying it? It sounds like a very worthwhile supplement to me. Be aware that the available strengths vary.... 4mg, 12 mg......and I'm sure others. In any event, it looks to be neuro-protective and at this point, anything I can do to alleviate the concern regarding my 4/4 status is welcome addition to my life! Didn't see this in any other subject on our apoe4 site so wanted to share!