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Choline Confusion

Alzheimer's, cardiovascular, and other chronic diseases; biomarkers, lifestyle, supplements, drugs, and health care.
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frankiesfriend
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Re: Choline Confusion

Postby frankiesfriend » Mon Nov 11, 2019 1:29 pm

I have been confused on this issue as well. I do want to lower my homocysteine from 9.8, but I have read that choline intake raised insulin resistance (appears to be an inconsistent result according the studies Julie cited), but also I think I have read that choline supplementation may raise cholesterol levels. Since high LDL is a problem for me (both LDL-C and LDL-P are high), I am at a crossroads. Which is more concerning...high cholesterol or high homocysteine? My second question has to do with which methyl donor to use when I do supplement if lowering homocysteine without raising other biomarkers is the goal. So do I take choline, or TMG, or PC, or betaine, or a little of each if meat intake is low? Right now, I switch back and forth, but I don't have any confidence that I know what I am doing. Each morning, I have numerous supplement bottles to choose from and I am always wondering if what I am taking is more harmful or helpful.

I am postmenopausal, and regarding this issue, genetics is working against me. Thank you for your insights.

frankiesfriend
E3/E4, My mother was diagnosed with AD at age 73.

BrianR
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Re: Choline Confusion

Postby BrianR » Mon Nov 11, 2019 4:42 pm

Julie G wrote:In defense of the authors, nutritional science is very difficult to conduct, especially from a longitudinal perspective. From this paper, however, I see no convincing evidence that dietary choline intake is correlated with mortality.

I don't want to be obnoxious and insist that "nutritional science" is an oxymoron. But, I guess I've reached the point where I read these studies for entertainment purposes, rather than as potential guidelines.

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Julie G
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Re: Choline Confusion

Postby Julie G » Mon Nov 11, 2019 5:36 pm

I don't want to be obnoxious and insist that "nutritional science" is an oxymoron. But, I guess I've reached the point where I read these studies for entertainment purposes, rather than as potential guidelines.

:lol: :lol: :lol:

circular
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Re: Choline Confusion

Postby circular » Mon Nov 11, 2019 6:58 pm

Julie G wrote:Hi Circ! I took a quick look at your latter study...

Thanks Julie! No worries about the graphic, just call me bat woman!
ApoE 3/4 > Thanks in advance for any responses made to my posts.


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