Chronically high levels of Myeloperoxidase

Alzheimer's, cardiovascular, and other chronic diseases; biomarkers, lifestyle, supplements, drugs, and health care.
Posts: 8
Joined: Wed Jan 25, 2017 3:59 am

Chronically high levels of Myeloperoxidase

Postby Sherpurvis » Fri Nov 22, 2019 5:42 am

My level of myeloperoxidase (MPO) are chronically high. Results from last (3) blood draws: 4145/4181/3523 mg/L. Shouldn’t be over 330! MPO is a antimicrobial enzyme released by activated neutrophils and monocytes and is a marker of inflammation and oxidative stress linked to endothelial dysfunction, atherosclerosis and coronary artery disease. That said, my hs-CRP is down to lowest levels ever, 0.3 mg/L (optimum), as well as Fibrinogen 457 mg/L (mildly elevated), and Lp-PLA2 Activity is the lowest as well at 163 mmoL/min/mL. My cholesterol is down 174 -pts! Been Keto for a year and a half, per Bredesen protocol, and have managed to get my lipid levels to their all time lowest levels as well. My issue is the MPO, I can’t seem to lower this dang marker! Any suggestions from this wonderful community?

Taking the following supplements/prescriptions:

NR (Elysium) which is nicotinimide riboside (250mg) and Pterostilbene (50mg)
Metformin (500mg) For longevity - 40% less chance of cancer
Levothyroxine (88mcg)
Liothyronine (5mcg)
Exetimibe (10mg) every other day
Apex Energetics Resvero 1/2 TB
Apex Energetics COQ10 1/2 TB
Gundry’s vital reds
Gundry’s primal plants
Calcium D Glutarate
Jarrow’s CDP-Choline
ProOmega 2000 fish oil
Methyl Protect 1 capsule/day
Miticore (2 capsules in morning and 2 in the evening)
Choleast 900 1 capsule at night
Ultraclear Renew - 1 scoop a day
Vitamin D3 with K2
Baby aspirin
Couple oz of Ikura salmon roe with avocado a couple days a week - Dr. Rhonda Patrick shows that fat in phospholipid forms gets through the blood brain barrier which is critical for APOE4/4

Do intermittent fasting 3-4 days a week and a prolonged fast 48-72 hours once a month.

Lastly, walk 6 miles on the beach ~ 4 days a week 3 weeks out of the month along with Pilates 2X per week.

User avatar
Posts: 2127
Joined: Wed Aug 03, 2016 6:20 pm
Location: Kentucky

Re: Chronically high levels of Myeloperoxidase

Postby slacker » Sun Nov 24, 2019 1:30 pm

Here is a Cleveland Clinic summary that includes ideas for further evaluation, just in case you haven't seen this list. Hope it helps!

Return to “Prevention and Treatment”

Who is online

Users browsing this forum: No registered users and 15 guests