R-enantiomer Carvedilol reverses AD in mice

Alzheimer's, cardiovascular, and other chronic diseases; biomarkers, lifestyle, supplements, drugs, and health care.
Post Reply
J11
Contributor
Contributor
Posts: 3351
Joined: Sat May 17, 2014 4:04 pm

R-enantiomer Carvedilol reverses AD in mice

Post by J11 »

Sorry everyone for posting so much though there is so much great AD news out there.
They reversed AD in mice with the R+ enantiomer of the widely prescribed generic anti-hypertensive Carvedilol?

Even in the presence of amyloid, the R+ enantiomer had anti-dementing effects.
Racemic Carvedilol (i.e., Coreg) would not be helpful for AD.



https://www.cell.com/cell-reports/pdfEx ... 20)31158-X
Top
J11
Contributor
Contributor
Posts: 3351
Joined: Sat May 17, 2014 4:04 pm

Re: R-enantiomer Carvedilol reverses AD in mice

Post by J11 »

This is interesting. This is the chemistry behind separating R and L enantiomers.

https://chem.libretexts.org/Bookshelves ... nantiomers
Top
Post Reply

Return to “Prevention and Treatment”