Alzheimers Dement. 2015 Feb 11. pii: S1552-5260(15)00017-5. doi: 10.1016/j.jalz.2014.11.009. [Epub ahead of print]
MIND diet associated with reduced incidence of Alzheimer's disease.
Morris MC1, Tangney CC2, Wang Y3, Sacks FM4, Bennett DA5, Aggarwal NT5.
In a previous study, higher concordance to the MIND diet, a hybrid Mediterranean-Dietary Approaches to Stop Hypertension diet, was associated with slower cognitive decline. In this study we related these three dietary patterns to incident Alzheimer's disease (AD).
We investigated the diet-AD relations in a prospective study of 923 participants, ages 58 to 98 years, followed on average 4.5 years. Diet was assessed by a semiquantitative food frequency questionnaire.
In adjusted proportional hazards models, the second (hazards ratio or HR = 0.65, 95% confidence interval or CI 0.44, 0.98) and highest tertiles (HR = 0.47, 95% CI 0.26, 0.76) of MIND diet scores had lower rates of AD versus tertile 1, whereas only the third tertiles of the DASH (HR = 0.61, 95% CI 0.38, 0.97) and Mediterranean (HR = 0.46, 95% CI 0.26, 0.79) diets were associated with lower AD rates.
High adherence to all three diets may reduce AD risk. Moderate adherence to the MIND diet may also decrease AD risk.
MIND Diet Associated with Reduced Incidence of Alzheimer’s Disease