Predimed Revisited...

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Julie G
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Re: Predimed Revisited...

Postby Julie G » Wed May 13, 2015 11:25 am

The new study has spurred me on to play with sofrito again. I have a big pot simmering now, but also found a great cold version for summer: http://latinfood.about.com/od/beginnerr ... osteps.htm
I can't wait to try this...so seasonal and chock full of antioxidants and phytonutrients!

Can anyone get full-text of the new study? It may reveal some additional clues.

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Stavia
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Re: Predimed Revisited...

Postby Stavia » Wed May 13, 2015 2:18 pm

Julie I only have my phone and we are about to depart for a small island off Vancouver for two days. Sorry honey :(

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Re: Predimed Revisited...

Postby Stavia » Wed May 13, 2015 2:42 pm

I've tried on my phone. Almost impossible. But I did find a predimed apoe subgroup analysis I sent to you.
Btw there are 45 subgroup analyses of predimed. Lol.

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Re: Predimed Revisited...

Postby ApropoE4 » Wed May 13, 2015 6:27 pm

Stavia wrote:I've tried on my phone. Almost impossible. But I did find a predimed apoe subgroup analysis I sent to you.
Btw there are 45 subgroup analyses of predimed. Lol.


It's easy to guess:

4/4 group too small and excluded from analysis.

3/4 group showed some (not significant) improvement, probably localized to some tests/brain areas

3/3 group showed significant improvement

right?

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Julie G
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Re: Predimed Revisited...

Postby Julie G » Wed May 13, 2015 6:53 pm

LOL, ApropoE4- you're not getting cynical on us, are you? ;) FWIW, you're probably pretty close. Here's the E4 paper that Stavia referenced. I had it linked to my initial post: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026432/

Stavia needs to have fun and not worry about this...but I'd greatly appreciate if someone else has access of the new paper and can share.

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Re: Predimed Revisited...

Postby ApropoE4 » Wed May 13, 2015 7:19 pm

Not cynical at all, but practically all of the dietary intervention/observation studies I've seen are like that.

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Stavia
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Re: Predimed Revisited...

Postby Stavia » Thu May 14, 2015 8:34 am

I've got hold of an ipad. Found it with great difficulty
I'll try email it to Julie

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Re: Predimed Revisited...

Postby Stavia » Thu May 14, 2015 8:46 am

Lots of e4s actually. 14 in each intervention group and 24 in the control. Results independent of e4 status. Julie you can have a good look and see what you think.

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Re: Predimed Revisited...

Postby Gilgamesh » Thu May 14, 2015 9:08 am

I'd love to see this paper if somone can email to me.

Note:

Interventions Participants were randomly assigned to a Mediterranean diet supplemented with extravirgin (sic) olive oil (1 L/wk), a Mediterranean diet supplemented with mixed nuts (30 g/d), or a control diet (advice to reduce dietary fat).

And look at the conflicts of interest (see the previous paper Julie linked to).

As I noted before, I wouldn't put a lot of stock in this research effort:

1) Massive conflicts of interest.

2) Olive oil is given at 140 g per day; nuts a tiny fraction of that.

3) The low-fat group wasn't very low-fat (despite the advice).

Somewhere I read it was 1 liter per family, but that's still imprecise, and, one would expect, in many cases, a lot.

I'll need to read the original protocol again. Our Richard had some good points on it (as did Michael Rae over at crsociety.org). Won't have access to my notes for a few days.

GB

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Re: Predimed Revisited...

Postby Stavia » Thu May 14, 2015 9:49 am

Emailed it a sec ago


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