Thanks for this LanceS, very interesting.
I’ve just been reading something about this on the IFLScience feed. A review of research on intermittent fasting, where one the variable was supplementing with antioxidants, (vitamins C and E) found this:
“One somewhat surprising finding is that when participants took daily oral supplements of Vitamin C and E, the benefits from fasting disappeared. It seems that because the cells were relatively sheltered from experiencing any oxidative stress that may have been caused by fasting every other day, they didn’t respond by increasing their natural defenses and improving their sensitivity to insulin and other stress signals.”
Not a big serious study, but the same as you write, this study suggests mitochondrial 'selection' or effectiveness with lots of antioxidant supplementation.
Think I'll change the way I take supplements and do fasting.
Here’s the link; http://www.iflscience.com/health-and-me ... ent-stress
(Warning in advance on the name of this site. The science is quite good though; popular science aimed at the 20+ graduate?).