I had a repeat CIMT today, a little over 7 months from the first one.
Gundry diet for me – generally follow his Matrix protocol with ApoE4 mods
Matrix diet w E4 mods 1-1-15.pdf
– minimal animal fat (including dairy), lots of unfiltered EVOO, shell and whitefish OK, with emphasis on shellfish.
Eat 2x/day – no snacks. Try to have at least 12 hours between evening meal and breakfast and 3 hours between evening meal and bed.
Breakfast might be 3 free-range eggs lightly cooked in unfiltered EVOO, 2 tbs psyllium husk hydrated in coconut milk with 1/2 cup blueberries & 2 squares of 86% cocao.
Evening meal, guacamole, steamed asparagus, baked plantain chips made from green plantains & unfiltered EVOO, shrimp, salad with spinach, chard, arugula, kale, broccoli, radish, green onion, carrots, parsley, cilantro, avocado, mushrooms, black olives, artichoke hearts, unfiltered EVOO, balsamic vinegar.
Well the CIMT results were behind door number 2 – no change (10-20% on one side, 20-30% on the other with an intima thickness 8 years older than my age). The PA (the practice has a LC focus and the MD is one of Jimmy Moore’s “experts”) was pleased and the short answer is to continue doing what I’m doing. We chatted about ApoE4, and slow saturated fat processing. I asked about high LDL-P in a low insulin environment. She said there was (of course) no data. She did say that, from a clinical standpoint, they rarely saw rapid calcification where elevated LDL was the only risk factor. Rapid calcification is almost always accompanied by diabetes or metabolic syndrome. When she looked at some of my NMR’s under various circumstances, she thought they all looked good (even the 404 below).
I did not pull a repeat NMR for this but here's some of the results from the standard profile I did pull a week ago. Fasting serum ketones 1.1, TC 231, Tg 70, HDL 54, LDL-C 164, glucose 84, insulin 3.8, A1C 5.3. I do test with a CardioCheck home monitor, using glass capillary tubes for sampling. I only sampled Tg's that morning & they were 66. Pretty much spot on with the lab test.
Here are some NMR's I pulled during the 7 months under varying conditions:
(LDL-P, Small LDL-P, HDL, Trig)
Whey protein, MCT, salad 1746, 404, 58, 61;
fasting 36 hours 1286, 237, 58, 94;
carb nite 1393, 206, 48, 55.
I think the reason she, Gundry & others still care about small LDL is because it represents Met Syndrome and insulin/glucose are the keys to problems, in their minds.
The PA said she thought I was doing very well, to keep on doing what I'm doing and to repeat the test in one year.
I did experiment with consuming 540 mcg/day of K2 as MK7. Obviously did not show reversal.
My Lp-PLA2 did increase from 218 to 278. Still puzzled about that. Before the test 7 months ago, my diet was a very traditional animal based LC/HF, with LOTS of saturated fat.
For the future, I'll stay the course, but may add some of the supps Gundry suggests.
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