Welp, dear hearts - because I have a 6/23 upcoming surgery scheduled (fibroid removal, minimally-invasive) - this is topically near to my heart.
My very astute gyny surgeon knows of my concerns re a general and suggested that I opt for conscious ("twilight" - IV) sedation with a local. AND I know that the best choice would probably be a local.
I most certainly do NOT want to be awake for this crap. And I found this:http://anesthesiology.pubs.asahq.org/Ar ... id=1933714
There is a strong association between ApoE4 and transient POCD in patients undergoing inhalation anesthesia. Compared with inhalation anesthesia, TIVA is more suitable for elderly patients because it has no observable effect on cognitive function of elderly patients after surgery, especially those carrying the ApoE ε4 allele.
which states that IV sedation is just dandy for us.
Thoughts??? Sigh. Hope everyone is doing swimmingly!!!
P.S. I even queried Rudy Tanzi. I've not heard from him yet. lol
P.P.S. I recall my poor 3/4 stepdad who, after carotid surgery (for which I'm quite certain he received a general), developed full-blown delirium upon waking. I think he was in his latter-60s. And then he started having AD symptoms...and that was probably not a coincidence. Cascade firestarter, and all that.
Perchance it's age- and 4-dose dependent? Because I had a general two-three times as a child.