Thanks, Susan. Boy, I've been going down the proverbial rabbit hole with this one
The prion theory has been around a long time. The idea that AD is transmittable is intriguing. Rudy Tanzi think's it's transmitted by eating meat. Given the profit-driven commercial feedlot system of meat production in the US...he may be on to something. Here's a nice overview of how the prion hypothesis has panned out from the 70s-present. http://dana.org/News/Details.aspx?id=43210
I thought there are experiments showing the only way to "transmit" AD was to implant Ab oglimer infested tissue directly into the target brain, which makes it not very transmittable at all. (and of course we know it's not transmittable because, you know, there are no epidemiological patterns supporting an even weakly transmittable nature)
Re. PrP antibodies - as far as I can remember, they need to be fed directly into the brain, which in turn tends to develop antibodies to try and fight them off, finally resulting in severe inflammation. Unlikely to be helpful, although they may prove a useful research tool.