I've noticed we have bits and pieces about melatonin floating around in
multiple threads. In an attempt to keep us organized, I've tried to compile relevant links and papers below:
From Spunky, an LEF article:
http://www.lef.org/magazine/mag2013/sep ... one_01.htm
Also from Spunky, another LEF article:
http://www.lef.org/magazine/mag2012/sep ... ors_01.htm
From Circular, a paper demonstrating melatonin's role in decreasing amyloid-beta plaque:
http://www.ncbi.nlm.nih.gov/m/pubmed/21354274/
Also, from Circular, a paper that outlines the positive effect melatonin may have
especially for E4 carriers:
http://www.experts.scival.com/indiana/p ... 13&o_id=22&
From Silver, a time released melatonin recommendation:
http://www.swansonvitamins.com/swanson- ... mg-60-tabs
Also From Silver, a report about a new study that found combining exercise with melatonin provided even more benefit against dementia:
http://www.sciencedaily.com/releases/20 ... 110110.htm
Another paper from Silver-
Clinical Aspects of Melatonin Intervention in Alzheimer's Disease Progression
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001215/
And, another paper from Silver-
Apolipoprotein E influences melatonin biosynthesis by regulating NAT and MAOA expression in C6 cells
http://onlinelibrary.wiley.com/doi/10.1 ... x/abstract
From Silver, another paper-
Reduced hippocampal MT2 melatonin receptor expression in Alzheimer’s disease This one is good in that E4 is specifically examined.
http://web1.sssup.it/pubblicazioni/ugov ... 5_1472.pdf
And (drum roll please!) a final paper from Silver-
Role of melatonin in Alzheimer-like neurodegeneration
http://www.melatonina.it/farma/download ... atonin.pdf
From Susan, a paper-
Clinical Aspects of Melatonin Intervention in Alzheimer’s Disease Progression
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001215/
Also from Susan, another paper-
Clinical Aspects of Melatonin Intervention in Alzheimer’s Disease Progression
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001215/
A caveat from Susan: I have chosen not to take melatonin - although RA patients show that their molecular machinery controlling the circadian rhythm is disturbed, melatonin does not help (and may hurt), whereas other autoimmune diseases improve.
And, a paper from Susan supporting her decision, but outlining positive effects on other autoimmune diseases-
Modulation by Melatonin of the Pathogenesis of Inflammatory Autoimmune Diseases
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709754/