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Show new changes starting from 03:06, 29 March 2024
   
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28 March 2024

     09:16  ApoE ε4 and health conditions besides (or maybe contributing to) Alzheimer’s‎‎ 3 changes history +6,364 [Theresab‎ (3×)]
     
09:16 (cur | prev) +490 Theresab talk contribs →‎Greater incidence of postoperative delirium: added Apolipoprotein E e4 allele does not increase the risk of early postoperative delirium after major surgery (Fernando José Abelha et al, 1 Feb 2012)
     
08:55 (cur | prev) +4,766 Theresab talk contribs →‎Post Operative Cognitive Decline (POCD) after General Anesthesia: added discussion and papers
     
08:31 (cur | prev) +1,108 Theresab talk contribs Started new subheading discussion: Post-Operative Cognitive Decline (POCD) after General Anesthesia
     09:05  Main Page diffhist +614 Theresab talk contribs elaborated on subjects discussed in Other Conditions besides (or maybe contributing to) Alzheimer's

27 March 2024

     18:31  ApoE ε4 and health conditions besides (or maybe contributing to) Alzheimer’s‎‎ 2 changes history +1,215 [Theresab‎ (2×)]
     
18:31 (cur | prev) +692 Theresab talk contribs →‎Greater incidence of postoperative delirium: added paper Apolipoprotein-E-e4-Allele-Increases-the-Risk-of Apolipoprotein E e4 Allele Increases the Risk of Early Postoperative Delirium in Older Patients Undergoing Noncardiac Surgery (Jacqueline M. Leung et al, Sep 2007)
     
18:28 (cur | prev) +523 Theresab talk contribs →‎Greater incidence of postoperative delirium: added explanation of delirium
     17:08  Beneficial (and some negative) Plant/Natural Chemicals diffhist +1,818 Theresab talk contribs →‎Fungi (mushrooms): added discussion of bioactive compounds in mushrooms

24 March 2024

 m   22:21  ApoE4-Aware Health Coaches diffhist +47 Nf52 talk contribs →‎Angela Balboa, BS Human Nutrition, Certified Functional Medicine Health Coach, Recode 2.0 Certified Coach, APOE4-Aware Health Coach

23 March 2024

     13:19  Beneficial (and some negative) Plant/Natural Chemicals diffhist +794 Theresab talk contribs →‎Terms K - O: added Oxyimperatorin (OIMP) to terms
     12:56  ApoE ε4 and health conditions besides (or maybe contributing to) Alzheimer’s diffhist +1,850 Theresab talk contribs added subheading: Greater incidence of postoperative delirium, and paper" Apolipoprotein E Genotype and the Association between C-reactive Protein and Postoperative Delirium: Importance of Gene-Protein Interactions (Sarinnapha M. Vasunilashorn et al, 1 Mar 2021),

21 March 2024

     07:37  Ketosis and Ketogenic Diet diffhist +1,300 Theresab talk contribs →‎Additional references on ketosis or the introduction of ketones on cognition /Alzheimer’s: added paper: Ketogenic diet and BHB rescue the fall of long-term potentiation in an Alzheimer’s mouse model and stimulates synaptic plasticity pathway enzymes (Jacopo Di Lucente et al, 16 Feb 2024)

19 March 2024

     14:29  Fats, Omega -3(ω-3) & -6(ω-6), DHA and More diffhist +1,700 Theresab talk contribs →‎A deeper dive into the science on Omega-3s: added paper: ''Baseline Findings of PreventE4: A Double-Blind Placebo Controlled Clinical Trial Testing High Dose DHA in APOE4 Carriers before the Onset of Dementia (Hussein Yassine et al, 19 June 2023) and reordered papers
     13:57  Insulin Resistance in the brain diffhist +845 Theresab talk contribs →‎A deeper dive into the science: added paper: State of the Science on Brain Insulin Resistance and Cognitive Decline Due to Alzheimer’s Disease' (Elizabeth M. Rhea et al, 2023)

18 March 2024

     08:15  Optimize antioxidants diffhist +124 Theresab talk contribs added cross reference to ApoE4.info wiki article: Beneficial (and some negative) Plant/Natural Chemicals
     08:09  Optimize mitochondrial function diffhist +84 Theresab talk contribs Added cross reference to ApoE4.info wiki article: Mitochondria
     08:06  Exercise‎‎ 2 changes history +108 [Theresab‎ (2×)]
     
08:06 (cur | prev) +33 Theresab talk contribs fixed crossreference from Stress to Exercise
     
08:00 (cur | prev) +75 Theresab talk contribs added cross reference to ApoE4.info wiki article: Stress
     08:03  GI health diffhist +135 Theresab talk contribs Added cross reference to ApoE4.info wiki: Gut-Brain Connection: Leaky Gut/Leaky Brain, Microbiome (gut bugs)
     07:46  Reduce stress‎‎ 2 changes history +74 [Theresab‎ (2×)]
     
07:46 (cur | prev) +74 Theresab talk contribs added cross reference to ApoE4.info wiki Stress
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07:44 (cur | prev) 0 Theresab talk contribs fixed typo
     07:43  Optimize sleep‎‎ 2 changes history +126 [Theresab‎ (2×)]
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07:43 (cur | prev) +12 Theresab talk contribs bold font
     
07:35 (cur | prev) +114 Theresab talk contribs added cross reference links to Sleep and Circadian Rhythm
     07:41  Enhance autophagy, ketogenesis diffhist +206 Theresab talk contribs added cross reference to ApoE4.info wiki articles "Ketosis and Ketogebic Diet" and Coconut Oil, MCT Oil, and other Ketone/Ccgnition boosters

15 March 2024

     07:44  Coffee (and caffeine)‎‎ 2 changes history +553 [Theresab‎ (2×)]
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07:44 (cur | prev) −95 Theresab talk contribs →‎Proposed mechanism(s): minor elimination
     
07:42 (cur | prev) +648 Theresab talk contribs →‎Proposed mechanism(s): added possible aluminum based neurotoxicity protection of caffeinated coffee and paper, Evaluating the Neuroprotective Potential of Caffeinated Coffee in the Context of Aluminum-Induced Neurotoxicity: Insights from a PC12 Cell Culture Model (Kamil Rodak et al, 13 Mar 2024)

14 March 2024

     09:02  Main Page diffhist +399 Theresab talk contribs →‎Introduction to APOE4: added paper, Cognitively healthy APOE4/4 carriers show white matter impairment associated with serum NfL and amyloid-PET (Claudia Tato-Fernández et al, Mar 2024) which found early white matter impairment in APOE4/4 homozygotes.
     08:45  Beneficial (and some negative) Plant/Natural Chemicals diffhist +1,231 Theresab talk contribs →‎Terms P - T: in term Trigonelline removed bad link and updated with newer research paper and elaborated more on benefits
     08:32  Coffee (and caffeine) diffhist +1,725 Theresab talk contribs →‎Proposed mechanism(s): added about trigonelline an alkaloid found in coffee and coffee byproducts

5 March 2024

     21:15  ApoE4-Aware Health Coaches diffhist +645 Nf52 talk contribs Added Julie Owen Morris, per email request

3 March 2024

     12:44  Beneficial (and some negative) Plant/Natural Chemicals diffhist +494 Theresab talk contribs →‎Terms P - T: added sulforaphane to terms
     12:40  ApoE ε4 and health conditions besides (or maybe contributing to) Alzheimer’s diffhist +219 Theresab talk contribs →‎Small Vessel Disease (SVD): added Dr Rhonda Patrick's article on Small Vessel Disease

2 March 2024

     15:05  Main Page‎‎ 5 changes history +1,019 [Theresab‎ (5×)]
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15:05 (cur | prev) +6 Theresab talk contribs →‎Introduction to APOE4: bold font
     
15:04 (cur | prev) +210 Theresab talk contribs →‎Introduction to APOE4: added source
     
15:00 (cur | prev) +84 Theresab talk contribs →‎Introduction to APOE4: added how FAD is different than LOAD at the cellular level
     
08:57 (cur | prev) −30 Theresab talk contribs →‎Introduction to APOE4: fixed caption
     
08:40 (cur | prev) +749 Theresab talk contribs →‎Introduction to APOE4: added subheadings to ease readability

1 March 2024

     16:11  ApoE ε4 and health conditions besides (or maybe contributing to) Alzheimer’s‎‎ 10 changes history +7,025 [Theresab‎ (10×)]
     
16:11 (cur | prev) +640 Theresab talk contribs →‎Decreased Longevity: added paper: Evaluation of genotype-specific survival using joint analysis of genetic and non-genetic subsamples of longitudinal data'''] (Konstantin G. Arbeev et al, Apr 2011)
     
16:08 (cur | prev) +586 Theresab talk contribs →‎Decreased Longevity: added paper: Trade-off in the effects of the apolipoprotein E polymorphism on the ages at onset of CVD and cancer influences human lifespan (Alexander M. Kulminski et al, Jun 2011)
     
16:05 (cur | prev) +707 Theresab talk contribs →‎Decreased Longevity: added paper: Effect of the APOE Polymorphism and Age Trajectories of Physiological Variables on Mortality: Application of Genetic Stochastic Process Model of Aging'''] (Konstantin G. Arbeev et al, 2 Jul 2012)
     
16:03 (cur | prev) +797 Theresab talk contribs →‎Decreased Longevity: added paper: Age, Gender, and Cancer but Not Neurodegenerative and Cardiovascular Diseases Strongly Modulate Systemic Effect of the Apolipoprotein E4 Allele on Lifespan'''] (Alexander M. Kulminski et al, Jan 2014)
     
16:01 (cur | prev) +702 Theresab talk contribs →‎Decreased Longevity: added paper: The ApoE gene is related with exceptional longevity: a systematic review and meta-analysis (Nuria Garatachean et al, Feb 2018)
     
15:58 (cur | prev) +915 Theresab talk contribs →‎Decreased Longevity: added paper: APOE Alleles and Extreme Human Longevity (Paola Sebastiani et al, Jan 2019)
     
15:55 (cur | prev) +686 Theresab talk contribs →‎Decreased Longevity: added paper: The Genetic Variability of APOE in Different Human Populations and Its Implications for Longevity'''] (Paolo Abondio et al, Mar 2019)
     
15:51 (cur | prev) +589 Theresab talk contribs →‎Decreased Longevity: added paper:Varying Effects of APOE Alleles on Extreme Longevity in European Ethnicities (Anastasia Gurinovich et al, Nov 2019)
     
15:48 (cur | prev) +706 Theresab talk contribs →‎Decreased Longevity: added paper: Understanding Alzheimer’s disease in the context of aging: Findings from applications of stochastic process models to the Health and Retirement Study (Konstantin G. Arbeev et al, Apr 2023)
     
15:44 (cur | prev) +697 Theresab talk contribs →‎Decreased Longevity: added paper: How are APOE4, changes in body weight, and longevity related? Insights from a causal mediation analysis'''] (Rachel Holmes et al, 1 Mar 2024)
 m   07:16  ApoE4-Aware Health Coaches‎‎ 2 changes history +39 [Nf52‎; Bookhound‎]
 m   
07:16 (cur | prev) +35 Nf52 talk contribs →‎Daniel Barber, MS, Certified ReCODE Health Coach, Functional Medicine Certified Health Coach, APOE4-Aware Health Coach
 m   
07:15 (cur | prev) +4 Bookhound talk contribs

29 February 2024

     14:28  ApoE4-Aware Health Coaches‎‎ 2 changes history +1,374 [Nf52‎ (2×)]
 m   
14:28 (cur | prev) +6 Nf52 talk contribs →‎Daniel Barber, MS, Certified ReCODE Health Coach, Functional Medicine Certified Health Coach, APOE4-Aware Health Coach
     
14:28 (cur | prev) +1,368 Nf52 talk contribs Daniel Barber addition per request to Health Coach wiki