Turmeric and curcumin

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Turmeric and, in particular, one of its components, curcumin have been studied as preventive measures against Alzheimer's. The evidence is so far promising, though still preliminary.

One problem with curcumin therapy is that most formulations appear not to result in sufficient quantities of curcumin being absorbed and crossing the blood-brain barrier.

ConsumerLab has recently reported that a new formulation of curcumin, CurcuWin (from OmniActive Health Technologies), has dramatically increased bioavailability:

A study funded by OmniActive found that Curcuwin increased curcuminoid levels in the blood plasma 4,490% above that achieved with standard curcumin (Jager, Nutr J 2014). The study also evaluated BCM-95 and Meriva, finding them, respectively, to increase total curcuminoid blood levels 30% and 690% above that with standard curcumin.

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Proposed mechanism(s)

Might APOE status affect relevance of the research supporting this intervention?

To Do

- Find more scientific review articles, ideally (as always), those that stratify results by APOE status.