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by Matisse
Thu Apr 30, 2020 10:02 pm
Forum: The Social Hour
Topic: Genetic Risk Factor for Covid-19
Replies: 15
Views: 2119

Re: Genetic Risk Factor for Covid-19

GemmaJ wrote:Hmmm...on 23andme it says that rs2070788 only has A and G variants so that's weird about the T variant.


T is the same as A, so all's well there. :D (And C is the same as G.)
by Matisse
Thu Apr 16, 2020 11:25 pm
Forum: Science and Research
Topic: KLOTHO: Good news for 20% of us!
Replies: 11
Views: 1945

Re: KLOTHO: Good news for 20% of us!

Julie, I believe those two snps are in linkage disequilibrium. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1534014/pdf/1471-2350-7-51.pdf Julie, the way I look at it, as an also-non-scientist, is that they travel together to a greater extent than chance. In this case they are in "perfect"...
by Matisse
Thu Apr 16, 2020 12:30 am
Forum: Science and Research
Topic: KLOTHO: Good news for 20% of us!
Replies: 11
Views: 1945

Re: KLOTHO: Good news for 20% of us!

Julie, I believe those two snps are in linkage disequilibrium.

https://www.ncbi.nlm.nih.gov/pmc/articl ... 0-7-51.pdf
by Matisse
Sun Jan 05, 2020 10:06 pm
Forum: Our Stories
Topic: Blood test for beta amyloid 42/40 ratio
Replies: 2
Views: 681

Re: Blood test for beta amyloid 42/40 ratio

Interesting but could be scary. What did it cost?
by Matisse
Mon Dec 30, 2019 8:17 pm
Forum: Getting Started
Topic: Apoe 4/4 and high triglycerides
Replies: 16
Views: 3116

Re: Apoe 4/4 and high triglycerides

My brother had very high trigs and is apoe3/3, so there may be more at work here than your apoe4 status. He was able to reduce his trigs with prescription fish oil.
by Matisse
Wed Oct 09, 2019 8:10 pm
Forum: Prevention and Treatment
Topic: Alzheimer’s Treatment with Julie Gregory (podcast w Dr. Carri)
Replies: 8
Views: 968

Re: Alzheimer’s Treatment with Julie Gregory (podcast w Dr. Carri)

Getting ready to listen to this one! Can't wait to hear what Julie Gregory has to share. Love it when she chimes in on here and truly love the forum she started! Thank you Julie. https://www.drcarri.com/alzheimers-treatment-with-julie-gregory/ Thanks for posting the link. I had read bit and pieces ...
by Matisse
Sat Aug 10, 2019 1:37 pm
Forum: Our Stories
Topic: I need help with my 23andme report...
Replies: 11
Views: 1664

Re: I need help with my 23andme report...

No, you have one 2 and one 4.
by Matisse
Sat Aug 10, 2019 9:18 am
Forum: Our Stories
Topic: I need help with my 23andme report...
Replies: 11
Views: 1664

Re: I need help with my 23andme report...

Unless your parents have been tested for apoe you have no way of knowing who you got each from. All you know is one parent has a 4 and one has a 2.
by Matisse
Fri Aug 09, 2019 10:13 pm
Forum: Our Stories
Topic: I need help with my 23andme report...
Replies: 11
Views: 1664

Re: I need help with my 23andme report...

Specifically, I need help with the Apoe4 report. I can't tell if I am a 3/4 or 4/4, or possibly, neither. Here is part of the report. It says I am "likely" an Apoe4 carrier. What can I conclude from this? Do I need further testing to determine if I am a 3/4 or 4/4, or neither? Thanks. APO...
by Matisse
Fri Jun 28, 2019 2:02 pm
Forum: Science and Research
Topic: New ApoE4 protective SNPs
Replies: 8
Views: 2016

Re: New ApoE4 protective SNPs

xactly wrote:
Matisse wrote:I don't see this on the V3, V4 or V5 platform of 23andme. How did you find it?

I was genotyped with the V3 chip. When I searched for the SNP in Raw Data, it showed up.


Thank you. I looked again and found it for a family member with V3 chip but not for any of us with V4 or V5.

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