Welcome Alicia! Hope you are finding information here that's helpful to you. Do you mind if I ask what the RS# is of the PSEN mutation you have? Did you get the results from 23andme or a physician's office? Do you have early onset dementia in your family? Perhaps you have already checked it all out,...

Have you tried contacting Dante Labs?

GemmaJ wrote:Hmmm...on 23andme it says that rs2070788 only has A and G variants so that's weird about the T variant.

T is the same as A, so all's well there. (And C is the same as G.)

Julie, I believe those two snps are in linkage disequilibrium. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1534014/pdf/1471-2350-7-51.pdf Julie, the way I look at it, as an also-non-scientist, is that they travel together to a greater extent than chance. In this case they are in "perfect"...

Julie, I believe those two snps are in linkage disequilibrium.

https://www.ncbi.nlm.nih.gov/pmc/articl ... 0-7-51.pdf

Interesting but could be scary. What did it cost?

My brother had very high trigs and is apoe3/3, so there may be more at work here than your apoe4 status. He was able to reduce his trigs with prescription fish oil.

Getting ready to listen to this one! Can't wait to hear what Julie Gregory has to share. Love it when she chimes in on here and truly love the forum she started! Thank you Julie. https://www.drcarri.com/alzheimers-treatment-with-julie-gregory/ Thanks for posting the link. I had read bit and pieces ...

No, you have one 2 and one 4.

Unless your parents have been tested for apoe you have no way of knowing who you got each from. All you know is one parent has a 4 and one has a 2.