A warm welcome to you from the members of ApoE4.Info!

You have found a group of people who are carriers of the APOE-ε4 allele, which forces us to grapple with elevated health risks including Alzheimer’s and cardiovascular disease. Some members are experiencing symptoms today, and others are caring for affected family or friends. We’re all searching for prevention and remediation strategies.

We know you may feel overwhelmed or even frightened. We created this community so that you don’t have to take this journey alone.

You can browse our website as a guest, and you can contribute as a member. We hope you’ll consider joining the conversation. You don’t need to be a medical professional, a scientist, or a researcher (although some members are) to participate. We believe everyone has a story and experiences that might be useful to someone else.

Inform Yourself

Learn the basics. We recommend our primer as the ideal starting place for your journey. Authored by a member physician who carries two copies of the APOE-ε4 allele, the primer thread offers accessible science background and prioritized, sensible preventative measures.

Consider testing. Learning one’s APOE-ε4 status can be life changing for you and your loved ones. Our Thinking About Testing? page identifies the issues to consider BEFORE you test.

Read some of our discussions. Poke around the forums to see what’s being discussed. The level of conversation can range from straightforward sharing of personal experiences and concerns to nuanced discussions about published research. Use our search to look for specific topics.

Join Us

Join the discussion. If you want to take part in the conversation, create a free account for yourself to become a member. When you join, please introduce yourself. You can share as much or as little as you like. And for tips and tricks to get the most out of our discussion forums, visit this handy guide.

Follow us on Facebook. For occasional summaries of important new research, follow our Facebook page.

Ask questions. If you’ve already looked for answers, you probably know there are no quick and easy solutions. The reality is that definitive one-size-fits-all advice for APOE-ε4 carriers doesn’t exist. Be skeptical of anyone who claims to have such information. As carriers of the gene ourselves, we fully acknowledge the many unknowns. We believe working on the cutting edge with the scientific community and sharing our own experiences and ideas with one another is our best path forward in our shared quest for answers.

If you spend some time with us, you’ll find a thoughtful, caring community. We look forward to hearing your story, and we hope that we can inspire one another to live our healthiest possible lives.