Wow Brian. I have trouble getting in to see my family doc in my small town. And you are doing international gene therapy trials. Nice.
I get it. Progress seems so slow. And I would consider the Lexeo trial myself.
Search found 640 matches
- Thu Apr 25, 2024 6:59 pm
- Forum: Science and Research
- Topic: Huge list of therapies / drugs in the pipeline
- Replies: 9
- Views: 24616
- Thu Apr 25, 2024 8:29 am
- Forum: Science and Research
- Topic: Huge list of therapies / drugs in the pipeline
- Replies: 9
- Views: 24616
Re: Huge list of therapies / drugs in the pipeline
Hi Brian - that's very interesting. Is the Lexeo trial moving slowly, and this is meant to speed things up?
- Wed Apr 24, 2024 6:27 pm
- Forum: Prevention and Treatment
- Topic: Let's solve ALZ. APOE4--Nature's/God's Original Design
- Replies: 15
- Views: 25931
Re: Let's solve ALZ. APOE4--Nature's/God's Original Design
Hi AnnieV, I appreciate your thinking. That the body evolved to function optimally and rest is up to us, to treat it well by eating right and living right. I spend a lot of time trying to do that myself, and I sure do hope it’s helping. It’s probably my training that causes me to think of evolution ...
- Wed Apr 24, 2024 10:30 am
- Forum: Prevention and Treatment
- Topic: Let's solve ALZ. APOE4--Nature's/God's Original Design
- Replies: 15
- Views: 25931
Re: Let's solve ALZ. APOE4--Nature's/God's Original Design
Hi everyone. I find all the trends and patterns fascinating and, like others, I look for useful clues there. Thanks for sharing those studies. But I keep coming but to the thought that I'm not sure it matters if apoe4 was or was not once beneficial, or if there are differences in risk across the glo...
- Fri Apr 12, 2024 8:56 am
- Forum: Science and Research
- Topic: talk about prevention strategies?
- Replies: 12
- Views: 55173
Re: talk about prevention strategies?
-Have you ever measured your homocysteine? That's an important biomarker to track as it's associated with cognitive decline, brain atrophy, white matter hyper intensities, etc. Most of us end up needing to supplement B-12, folate and B6 (as P5P). Below is a quote homocysteine from "Breaking Al...
- Fri Apr 12, 2024 8:52 am
- Forum: Science and Research
- Topic: talk about prevention strategies?
- Replies: 12
- Views: 55173
Re: talk about prevention strategies?
Oh are you a mouth breather too? :) Does taping work? Yes, absolutely! About six years ago, just as I was entering menopause and my estrogen was dropping, I started having severe sleep problems and would wake up many times a night. I started myofunctional therapy and joined a breathing clinic, and ...
- Tue Apr 09, 2024 11:44 am
- Forum: Science and Research
- Topic: talk about prevention strategies?
- Replies: 12
- Views: 55173
Re: talk about prevention strategies?
Hi Julie, Thanks for your message. I hope all is well. -E4, in a dose dependent fashion, has been shown to impair the brain's ability to effectively use glucose — hence the importance of getting into ketosis at least once daily (1.0-1.5 mM), not chronically. (Read more here. ) Have you ever measured...
- Tue Apr 09, 2024 11:26 am
- Forum: Science and Research
- Topic: talk about prevention strategies?
- Replies: 12
- Views: 55173
Re: talk about prevention strategies?
Hi Plumster, thanks for sharing your plan. Whole foods plant based diet low fat, low sugar At various times, sometime lasting for years, I've done the Med Diet and ketoflex variations, with or without 16h fasting. Recently I've been really convinced that ketogenic diets have good benefits, so I went...
- Sun Apr 07, 2024 2:14 pm
- Forum: Science and Research
- Topic: talk about prevention strategies?
- Replies: 12
- Views: 55173
talk about prevention strategies?
Hi everyone, I hope all is well. Anyone want to talk about prevention strategies? Here’s mine: Fish oil, vitamin D, atorvastatin 10mg sulforaphane and sodium butyrate, hoping these HDAC inhibitors fix endosomal/lysosomal cycling. Tried homotaurine for a while, would like to restart that. A generally...
- Sun Apr 07, 2024 1:51 pm
- Forum: Science and Research
- Topic: Article: APOE loss of function: A genetic shield against Alzheimer’s disease
- Replies: 1
- Views: 32354
Re: Article: APOE loss of function: A genetic shield against Alzheimer’s disease
Hi. I was just reading these. Seems like an opportunity for RNAi or using an antibody (which can get through the BBB) to shut apoe4 down. Sign me up!