Here is another link that shows how a 14% allele frequency results in a 26% genotype frequency
http://www.alzgene.org/meta.asp?geneID=83
(numbers base on European heritage since that is my area of interest)

My wife got confirmation of her E4 status through Life Extension and it matched 23 and Me. LE used Kashi lab. You get a few simple sterile swabs that you air dry and return. The Life Extension doctor shows as the ordering physician on the report. The report is several pages giving the result and som...

I haven't seen any data that suggests that the statement: "13-16% of people of European descent, ... carry at least one copy of the ε4variant" 14% is commonly cited as the allele frequency. That's different since each individual will have 2 Here is a link of actual population prevalence: h...

In the second sentence of that paragraph aren't they are citing allele frequencies? That is for Europeans 14-16%. Then that would make sense with the observed 26% e4 genotype in the table

23 and me sent me this link. I think it has an error https://permalinks.23andme.com/pdf/PN-20-0234.pdf
Allele frequency vs genotype frequency

Hi Susan, do you have a link specifically about the testing zinc levels? Your link doesn't mention it. The AREDS report 1 doesn't mention it. I haven't read all of the reports. rianlees, I am interested in zinc copper ratios. If you have a reference on testingI would be interested. If it turns out t...

So the NIH doesn't think serum or plasma zinc levels correlate with tissue levels but the report also doesn't give me much confidence in the value of testing. Zinc supplements may be beneficial for age related macular degeneration but they just supplemented w/o testing from what I can tell from the ...

I would like to learn more about that. Do you have a source of information?

I think the simple measures like healthy food exercise and positivity will pay off the most in the long run.

Hermione, I agree 100%. FWIW I am pretty sure Ancestry would say they don't want you to do Promethease but a nonresult would be better than a wrong one. I haven't had a response from Promethease. They got back to me quickly on a technical web related issue. I suspect that I may not get a response. I...