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by Epsilon?
Tue Jul 03, 2018 4:50 pm
Forum: Our Stories
Topic: APOE mismatch Ancestry vs 23andMe
Replies: 25
Views: 8736

Re: APOE mismatch Ancestry vs 23andMe

Here is another link that shows how a 14% allele frequency results in a 26% genotype frequency
http://www.alzgene.org/meta.asp?geneID=83
(numbers base on European heritage since that is my area of interest)
by Epsilon?
Wed Jun 13, 2018 4:03 am
Forum: Our Stories
Topic: APOE mismatch Ancestry vs 23andMe
Replies: 25
Views: 8736

Re: APOE mismatch Ancestry vs 23andMe

My wife got confirmation of her E4 status through Life Extension and it matched 23 and Me. LE used Kashi lab. You get a few simple sterile swabs that you air dry and return. The Life Extension doctor shows as the ordering physician on the report. The report is several pages giving the result and som...
by Epsilon?
Tue Jun 12, 2018 6:31 pm
Forum: Our Stories
Topic: APOE mismatch Ancestry vs 23andMe
Replies: 25
Views: 8736

Re: APOE mismatch Ancestry vs 23andMe

I haven't seen any data that suggests that the statement: "13-16% of people of European descent, ... carry at least one copy of the ε4variant" 14% is commonly cited as the allele frequency. That's different since each individual will have 2 Here is a link of actual population prevalence: h...
by Epsilon?
Tue Jun 05, 2018 4:36 am
Forum: Our Stories
Topic: APOE mismatch Ancestry vs 23andMe
Replies: 25
Views: 8736

Re: APOE mismatch Ancestry vs 23andMe

In the second sentence of that paragraph aren't they are citing allele frequencies? That is for Europeans 14-16%. Then that would make sense with the observed 26% e4 genotype in the table
by Epsilon?
Mon May 28, 2018 2:52 pm
Forum: Our Stories
Topic: APOE mismatch Ancestry vs 23andMe
Replies: 25
Views: 8736

Re: APOE mismatch Ancestry vs 23andMe

23 and me sent me this link. I think it has an error https://permalinks.23andme.com/pdf/PN-20-0234.pdf
Allele frequency vs genotype frequency
by Epsilon?
Mon May 28, 2018 2:45 pm
Forum: Prevention and Treatment
Topic: Zinc : Serum vs RBC
Replies: 7
Views: 3332

Re: Zinc : Serum vs RBC

Hi Susan, do you have a link specifically about the testing zinc levels? Your link doesn't mention it. The AREDS report 1 doesn't mention it. I haven't read all of the reports. rianlees, I am interested in zinc copper ratios. If you have a reference on testingI would be interested. If it turns out t...
by Epsilon?
Sun May 27, 2018 6:38 pm
Forum: Prevention and Treatment
Topic: Zinc : Serum vs RBC
Replies: 7
Views: 3332

Re: Zinc : Serum vs RBC

So the NIH doesn't think serum or plasma zinc levels correlate with tissue levels but the report also doesn't give me much confidence in the value of testing. Zinc supplements may be beneficial for age related macular degeneration but they just supplemented w/o testing from what I can tell from the ...
by Epsilon?
Wed May 23, 2018 5:03 am
Forum: Prevention and Treatment
Topic: Zinc : Serum vs RBC
Replies: 7
Views: 3332

Re: Zinc : Serum vs RBC

I would like to learn more about that. Do you have a source of information?
by Epsilon?
Tue May 22, 2018 5:28 pm
Forum: Prevention and Treatment
Topic: Simple changes support thread
Replies: 16
Views: 3850

Re: Simple changes support thread

I think the simple measures like healthy food exercise and positivity will pay off the most in the long run.
by Epsilon?
Mon May 21, 2018 6:24 am
Forum: Our Stories
Topic: APOE mismatch Ancestry vs 23andMe
Replies: 25
Views: 8736

Re: APOE mismatch Ancestry vs 23andMe

Hermione, I agree 100%. FWIW I am pretty sure Ancestry would say they don't want you to do Promethease but a nonresult would be better than a wrong one. I haven't had a response from Promethease. They got back to me quickly on a technical web related issue. I suspect that I may not get a response. I...

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