I thought this was of interest: "Although carbohydrates are the only food constituents that directly increase blood glucose (the main determinant of insulin secretion), population studies suggest that the total amount of carbohydrate as a percentage of dietary energy is less important than the ...

Interesting new article in the BMJ Dietary carbohydrates: role of quality and quantity in chronic disease David S Ludwig and colleagues examine the links between different types of carbohydrates and health Carbohydrate is the only macronutrient with no established minimum requirement. Although many ...

This looked of interest on this topic https://www.bmj.com/content/361/bmj.k2340 Dietary carbohydrates: role of quality and quantity in chronic disease David S Ludwig and colleagues examine the links between different types of carbohydrates and health Carbohydrate is the only macronutrient with no es...

A first-of-its-kind study has found that 'skinny fat' -- the combination of low muscle mass and strength in the context of high fat mass -- may be an important predictor of cognitive performance in older adults. Using data from a series of community-based aging and memory studies, researchers assess...

Hi Gemma, I've got similar cholesterol levels to you have inn the first set of results, (HDL over 100, LDL in 70s, and low trigs) I do eat some grains and small amount of oats, like the med diet but with intermittent fasting. It's good the HDL is still high though. maybe you just need to tweak thing...

I too can't afford all that nor is it available in my country. It's almost a relief. not to have the financial stress and that of all the tests etc. I'd rather spend my little money on basic vitamins, eat well and get a gym membership. Oh and the local library is free to read books and improve my mi...

Interesting and quite recent article on BDNF and fluoxetine, isn't BDNF linked with AD I remember? And low BDNF and depression is definitely linked with the start of AD... https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642497/ Beneficial effect of fluoxetine treatment aganist psychological stress is ...

Hi yes there are others, - and some which seem to be higher magnitude than the previously mentioned, for example I have got a variant this one https://www.snpedia.com/index.php/rs4149268 and this https://www.snpedia.com/index.php/rs4149274 Also these is a mention of this on promethease, and I've got...

Final update: Managed to find a balance by having a tiny amount of prozac a day, a few mg measured out. Going to continue this and am feeling much better. Little side effects and less withdrawal problems (palpitations etc all gone)

Regarding ABCA1, it is possible to look at the variants on Promethease, for this. It says things like associated with higher HDL...so there must be an association there with that as well. I wonder if you have good variants for ABCA1 that might help the lipidation of the APOE4? (hopeful :roll: ) For ...