Here is an interesting article from Harvard Medicine on "Inflammation and Brain Health" that correlates to this discussion on using exercise to reduce brain inflammation.
https://hms.harvard.edu/magazine/aging/ ... ain-health
Search found 57 matches
- Fri Dec 10, 2021 8:35 am
- Forum: Science and Research
- Topic: Microglial correlates of late life physical activity
- Replies: 2
- Views: 766
- Wed Nov 17, 2021 8:02 pm
- Forum: Prevention and Treatment
- Topic: Blood Test for Amyloid in BAN2401 AD Prevention trial
- Replies: 2
- Views: 561
Re: Blood Test for Amyloid in BAN2401 AD Prevention trial
Thanks NF52 for this report. There is another trial, "Trailblazer-ALZ" that is also looking at using a monoclonal antibody as a preventative therapy for persons at high risk for Alzheimer's. The Trailblazer trial uses a Lilly drug called donanemab while the trial you refer to uses a drug c...
- Mon Oct 11, 2021 4:41 pm
- Forum: Science and Research
- Topic: Bumetanide for APOE4 Carriers
- Replies: 7
- Views: 6661
Bumetanide for APOE4 Carriers
Interesting article in "Nature Aging". In this research done by the Gladstone Institute, bumetanide, a common diuretic was found to reduce the instance of AD in APOE4 carriers. "A commonly available oral diuretic pill approved by the U.S. Food and Drug Administration may be a potentia...
- Sat Jun 13, 2020 10:56 am
- Forum: Science and Research
- Topic: New Research on Blood Brain Barrier and APOE4
- Replies: 13
- Views: 6963
Re: New Research on Blood Brain Barrier and APOE4
There are research groups studying the drug rapamycin for potential efficacy in "life extension". If I had to guess, this particular anti-rejection drug could be the one referred to in the first post.
- Fri Jun 12, 2020 9:50 am
- Forum: Science and Research
- Topic: New Research on Blood Brain Barrier and APOE4
- Replies: 13
- Views: 6963
Re: New Research on Blood Brain Barrier and APOE4
Took a look at the article Published: 29 April 2020 APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline Axel Montagne, Daniel A. Nation, […]Berislav V. Zlokovic Nature volume 581, pages71–76(2020) There is no mention that I can find regarding these small molecules. I will che...
- Mon Feb 03, 2020 4:56 pm
- Forum: Science and Research
- Topic: Plant flavonols significantly reduce Alzheimer’s risk
- Replies: 8
- Views: 3187
Re: Plant flavonols significantly reduce Alzheimer’s risk
Yes. I'll copy the text over to here so folks can have a look. A new paper in the journal Neurology looks at the multi-year effects of dietary flavonols on Alzheimer's. http://dx.doi.org/10.1212/WNL.0000000000008981 In this study, 921 participants with no initial dementia were followed over several ...
- Sat Feb 01, 2020 11:32 am
- Forum: Prevention and Treatment
- Topic: NR and NMN
- Replies: 20
- Views: 8622
Re: NR and NMN
I have been taking 150 mg of NR (Niagen) for about one year. No changes in my bloodwork. Upped the dose to 300 mg, then 900 mg about one month ago. I did not notice any changes in how I feel or sleep with the dosage increase. Have not had bloodwork on the higher dose yet. Found NMN on Alibaba (China...
- Fri Jan 31, 2020 1:19 pm
- Forum: Science and Research
- Topic: Plant flavonols significantly reduce Alzheimer’s risk
- Replies: 8
- Views: 3187
Dietary Flavonols
A new paper in the journal Neurology looks at the multi-year effects of dietary flavonols on Alzheimer's. http://dx.doi.org/10.1212/WNL.0000000000008981 In this study, 921 participants with no initial dementia were followed over several years, with 220 of those persons ultimately developing dementia...
- Mon Jan 06, 2020 10:20 am
- Forum: Science and Research
- Topic: 2019 Year in Review
- Replies: 3
- Views: 1563
2019 Year in Review
Here is an article reviewing Alzheimer's research throughout 2019. It is a long, very interesting read covering a wide diversity of AD research topics and ideas that show some promise.
https://www.alzforum.org/news/research- ... s-research
https://www.alzforum.org/news/research- ... s-research
- Tue Dec 03, 2019 12:28 pm
- Forum: Prevention and Treatment
- Topic: Carbohydrates and Longevity
- Replies: 16
- Views: 5144