No, I mean the extended time release is not the stuff to use. Slo-Niacin is OK, I believe it is in a wax matrix that dissolves fairly slowly. Also, from my notes "A dose of timed release = 2x dose of plain niacin. So 1 g Slo Niacin = 2g plain niacin."alysson wrote:GeorgeN wrote:I took niacin for a while, a gram/day. Usually Slo-Niacin brand. Initially did have a strong flush reaction, but later it was mild and I didn't mind it at all. From what I've read, you don't want it to be too spread out as spreading it over time has a negative effect on the liver. In any case, I'd not taken niacin for many months.George, when you say niacin shouldn't be too spread out, do you mean you shouldn't stop and start it from day to day or week to week? I was told to take it daily and not stop because I'd have to start over at square 1 when I restarted it. Of course, I did stop the niacin for a few weeks because that reaction I had scared me. So I had to start over.
I decided to do a "detox" using exercise, sauna & niacin. I selected (randomly) 3 grams of niacin as nicotinic acid as my dose - no delay. I went to the gym and started to lift. Had barely started and figured this was not going to happen, started feeling bad. Went and sat on the john. Nearly passed out. Was sweating, weak and felt awful. But it was passable if I kept my head by my knees. Finally felt good enough to make it over to a quiet area near a racquetball court where I could get prone on the carpet for a while without attracting attention. I knew it was an extreme flush reaction and would pass. It did. I then did go sit in the sauna for a while. I was fine once the flush was over. I also knew I'd played with way too high a dose, since I wasn't used to it. I have not repeated the fun...
Doesn't mean I won't repeat - just will be a little saner about my starting dose...How awful to have this extreme flush reaction in a public setting. I can see why you haven't repeated that experiment. But what you experienced is consistent with the physical symptoms I felt.
Also know that niacin will increase glucose (never had it increase ketones out of the range of reason). Gundry told us this is well known and not an issue. I think it stimulates the liver to release glycogen.
In the detox notes, it is supposed to stimulate lipolysis (break down of fats) - this could also increase ketones??? Also the intent of the exercise and sauna. The detox idea is to clear accumulated "toxins" from fax cells. See this and this from a Dr. Yu who has worked with the flush.It's interesting that niacin stimulates the liver to release glycogen. I have often wondered if my liver glycogen stores become depleted and that's why I was waking up hungry in the middle of the night. So if I didn't have liver glycogen stores available for niacin to stimulate, I wonder if that could increase ketone production.
I'm sending an email to you with info from a niacin book.
But it's good you'll be saner with your dosing.
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