Difference between revisions of "Fasting insulin less than 5; HgbA1c less than 5.6"

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(updated A1c level based on recent interview)
 
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The tenth intervention to reverse mild Alzheimer's in the [[Bredesen Protocol]] is:
 
The tenth intervention to reverse mild Alzheimer's in the [[Bredesen Protocol]] is:
  
:'''Goal''' Fasting insulin <5 uIU/ml; HgbA1c <5.6% (earlier version of the protocol was Fasting insulin <7; HgbA1c <5.5)
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:'''Goal''' Fasting insulin <5 uIU/ml; HgbA1c of 4.5 to 5.2 (in his book The End of Alzheimer's Dr Bredesen calls for an HgbA1c of less than 5.6, however, from a May 2019 interview, he is now citing a desired range of 4.5 to 5.2); Fasting Glucose below 90.
  
 
:'''Approach''' Diet as above
 
:'''Approach''' Diet as above
  
:'''Rationale''' Type II diabetes-AD relationship
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:'''Rationale''' Type II diabetes-AD relationship, glycotoxicity
  
HgbA1c ([http://en.wikipedia.org/wiki/Glycated_hemoglobin Glycated hemoglobin)] gives you an indication of your average glucose over the past 1-2 months and is better than a spot check of your glucose.  It is helpful to know the hemoglobin A1c, the [http://labtestsonline.org/understanding/analytes/insulin/tab/test/ fasting insulin], and the [http://labtestsonline.org/understanding/analytes/glucose/tab/test/ fasting glucose], since these offer complementary information.  Hemoglobin A1c should be less than 5.6%, fasting blood glucose should be less than 90 mg/dl, and fasting insulin should be less than 5 ulU/ml.  These are critical for optimal cognitive function.
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HgbA1c ([http://en.wikipedia.org/wiki/Glycated_hemoglobin Glycated hemoglobin)] also known as HbA1c or just A1c, gives you an indication of your average glucose over the past 1-2 months and is better than a spot check of your glucose.  It is helpful to know the hemoglobin A1c, the [http://labtestsonline.org/understanding/analytes/insulin/tab/test/ fasting insulin], and the [http://labtestsonline.org/understanding/analytes/glucose/tab/test/ fasting glucose], since these offer complementary information.  Hemoglobin A1c should be less than 5.3%, fasting blood glucose should be less than 90 mg/dl, and fasting insulin should be less than 5 ulU/ml.  These are critical for optimal cognitive function.
  
 
Avoid simple carbohydrates and high glycemic index foods; [[exercise]] regularly; and take [http://www.alzheimers.net/2014-07-02/cinnamon-prevents-alzheimers cinnamon], [http://alzdiscovery.org/cognitive-vitality/report/ala alpha-lipoic acid], [http://www.ncbi.nlm.nih.gov/pubmed/20423560 chromium picolinate], and  [http://onlinelibrary.wiley.com/doi/10.1002/brb3.208/full N-acetyl cysteine] each day.
 
Avoid simple carbohydrates and high glycemic index foods; [[exercise]] regularly; and take [http://www.alzheimers.net/2014-07-02/cinnamon-prevents-alzheimers cinnamon], [http://alzdiscovery.org/cognitive-vitality/report/ala alpha-lipoic acid], [http://www.ncbi.nlm.nih.gov/pubmed/20423560 chromium picolinate], and  [http://onlinelibrary.wiley.com/doi/10.1002/brb3.208/full N-acetyl cysteine] each day.
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* [https://www.apoe4.info/forums/download/file.php?id=453 Improving and Retaining Memory Function] Feb 15, 2015
 
* [https://www.apoe4.info/forums/download/file.php?id=453 Improving and Retaining Memory Function] Feb 15, 2015
 
* [http://en.wikipedia.org/wiki/Diabetes_mellitus_type_2 Type II diabetes]
 
* [http://en.wikipedia.org/wiki/Diabetes_mellitus_type_2 Type II diabetes]
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* [[Insulin Resistance in the brain]]
  
 
== Next Intervention ==
 
== Next Intervention ==
  
 
The next intervention in the [[Bredesen Protocol]] is [[Hormone balance]].
 
The next intervention in the [[Bredesen Protocol]] is [[Hormone balance]].

Latest revision as of 08:59, 12 June 2019

The tenth intervention to reverse mild Alzheimer's in the Bredesen Protocol is:

Goal Fasting insulin <5 uIU/ml; HgbA1c of 4.5 to 5.2 (in his book The End of Alzheimer's Dr Bredesen calls for an HgbA1c of less than 5.6, however, from a May 2019 interview, he is now citing a desired range of 4.5 to 5.2); Fasting Glucose below 90.
Approach Diet as above
Rationale Type II diabetes-AD relationship, glycotoxicity

HgbA1c (Glycated hemoglobin) also known as HbA1c or just A1c, gives you an indication of your average glucose over the past 1-2 months and is better than a spot check of your glucose. It is helpful to know the hemoglobin A1c, the fasting insulin, and the fasting glucose, since these offer complementary information. Hemoglobin A1c should be less than 5.3%, fasting blood glucose should be less than 90 mg/dl, and fasting insulin should be less than 5 ulU/ml. These are critical for optimal cognitive function.

Avoid simple carbohydrates and high glycemic index foods; exercise regularly; and take cinnamon, alpha-lipoic acid, chromium picolinate, and N-acetyl cysteine each day.

Optimize diet.

References

Next Intervention

The next intervention in the Bredesen Protocol is Hormone balance.